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β-环糊精对犊牛隐孢子虫自然感染的评估。

Evaluation of beta-cyclodextrin against natural infections of cryptosporidiosis in calves.

作者信息

Castro-Hermida J A, González-Losada Y, Freire-Santos F, Mezo-Menéndez M, Ares-Mazás E

机构信息

Laboratorio de Parasitología, Departamento de Microbiología y Parasitología, Facultad de Farmacia, Universidad de Santiago de Compostela, Avda. de Vigo s/n, 15782 Santiago de Compostela, La Coruña, Spain.

出版信息

Vet Parasitol. 2001 Nov 5;101(2):85-9. doi: 10.1016/s0304-4017(01)00505-2.

Abstract

The effectiveness of beta-cyclodextrin, excipient used in pharmaceutical industry, in the treatment of natural infection by Cryptosporidium parvum in suckling calves, was evaluated. Administration of the drug at a dose of 500 mg/kg body weight for 3 consecutive days from birth (prophylactically) or following confirmation of the infection (therapeutically) decreased the severity of diarrhoea and shortened the duration of oocyst shedding.

摘要

对制药行业中使用的辅料β-环糊精治疗哺乳犊牛自然感染微小隐孢子虫的效果进行了评估。从出生起连续3天以500毫克/千克体重的剂量给药(预防性给药),或在确认感染后给药(治疗性给药),均可减轻腹泻的严重程度,并缩短卵囊排出的持续时间。

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