对于浸润性乳腺癌，在乳房切除术后采用来自腹部的游离皮瓣进行乳房重建在肿瘤学上是安全的。

Breast reconstruction following mastectomy for invasive breast cancer by free flaps from the abdomen is oncologically safe.

作者信息

Snoj M, Arnez Z M, Sadikov A, Suvorov N

机构信息

Institute of Oncology, Department of Surgery, Zaloska 2, 1000 Ljubljana, Slovenia.

出版信息

Eur J Surg Oncol. 2007 Jun;33(5):541-5. doi: 10.1016/j.ejso.2006.11.024. Epub 2006 Dec 28.

DOI:10.1016/j.ejso.2006.11.024

PMID:17196363

Abstract

AIMS

To report the long-term results of oncological safety of breast reconstruction by autologous tissue following mastectomy for invasive breast cancer.

METHODS

One-hundred-fifty-six consecutive patients with invasive breast cancer treated with mastectomy and reconstruction by autologous tissue were reviewed throughout (from 1987 to 2003 with median follow up time of 66 months).

RESULTS

Median patient age was 45.9 years (range 26-68). The 157 observed tumors had mean diameter of 25+/-19 mm, 70 of them were poorly differentiated, and 137 were invasive ductal carcinoma. Multifocal disease was present in 44 patients. Breast reconstruction was carried out only by autologous tissue (free flaps were used in 95% and free TRAM flap transfer was the most common reconstructive procedure). There was only one local recurrence as first site of recurrence, thus yielding a local recurrence rate of 0.6%.

CONCLUSIONS

Breast reconstruction by autologous tissue following mastectomy for invasive breast cancer is an oncologically safe procedure.

摘要

目的

报告浸润性乳腺癌乳房切除术后采用自体组织进行乳房重建的肿瘤学安全性的长期结果。

方法

回顾性分析156例连续接受乳房切除及自体组织重建的浸润性乳腺癌患者（时间跨度为1987年至2003年，中位随访时间为66个月）。

结果

患者中位年龄为45.9岁（范围26 - 68岁）。观察到的157个肿瘤平均直径为25±19mm，其中70个为低分化，137个为浸润性导管癌。44例患者存在多灶性病变。仅采用自体组织进行乳房重建（95%采用游离皮瓣，游离腹直肌肌皮瓣转移是最常见的重建手术）。仅1例局部复发为复发的首发部位，因此局部复发率为0.6%。