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目前儿童肠套叠治疗的成功情况。

Current success in the treatment of intussusception in children.

作者信息

Kaiser Anthony D, Applegate Kimberly E, Ladd Alan P

机构信息

Department of Surgery, Indiana University School of Medicine, Indianapolis, Indiana, USA.

出版信息

Surgery. 2007 Oct;142(4):469-75; discussion 475-7. doi: 10.1016/j.surg.2007.07.015.

Abstract

BACKGROUND

Intussusception remains a common cause of bowel obstruction in young children and results in significant morbidity and mortality if not promptly treated. The goal of this study was to determine the current success rate of radiologic reduction, the requirements for operative intervention, and the effect of delay in presentation on outcome.

METHODS

Children treated for intussusception over a 15-year period were reviewed after treatment at a tertiary children's hospital. Records were reviewed for patient outcomes from radiologic evaluation and surgical intervention.

RESULTS

Two hundred forty-four children with intussusception were identified. Median age was 8.2 months (range, 16 days to 12.7 years). Eighty-seven percent of patients had ileocolic or ileoileocolic intussusception. The most common presenting symptoms were emesis (81%), hematochezia (61%), and abdominal pain (59%). Contrasted enemas were performed in 190 children, with successful reduction in 46%. Air-contrasted enema reduction was more successful than liquid-contrasted techniques (54% vs 34%; P = .017). Success in reduction was greater if symptom duration was <24 hours compared with >24 hours (59% vs 36%; P = .001). Despite failed prior attempts at reduction, 48% were reduced on reattempted enema reduction. One hundred forty children required surgical intervention for intussusception with 50% requiring bowel resection. Children with symptom duration >24 hours had a greater risk of requiring surgery (73% vs 45%; P < .001) and bowel resection (39% vs 17%; P = .001) than those with symptoms for <24 hours. Pathologic lead points were encountered in 14%. There were 2 deaths and complications occurred in 19%. Length of stay after surgical reduction was 3.9 days, but 6.1 days if bowel resection was required.

CONCLUSIONS

Success of intussusception reduction is improved with air-contrasted techniques and is not affected by previously failed, outside attempts. Delay in presentation decreases success in radiologic reduction and increases risk of operative intervention and bowel resection.

摘要

背景

肠套叠仍是幼儿肠梗阻的常见原因,若不及时治疗会导致显著的发病率和死亡率。本研究的目的是确定目前放射学复位的成功率、手术干预的要求以及就诊延迟对预后的影响。

方法

对一家三级儿童医院15年间接受肠套叠治疗的儿童在治疗后进行回顾。审查记录以了解放射学评估和手术干预的患者预后情况。

结果

共确定244例肠套叠患儿。中位年龄为8.2个月(范围16天至12.7岁)。87%的患者为回结肠或回结回肠套叠。最常见的症状为呕吐(81%)、便血(61%)和腹痛(59%)。190例患儿接受了对比灌肠,复位成功46%。空气对比灌肠复位比液体对比技术更成功(54%对34%;P = 0.017)。症状持续时间<24小时的复位成功率高于>24小时的(59%对36%;P = 0.001)。尽管先前复位尝试失败,但再次灌肠复位时48%成功。140例患儿因肠套叠需要手术干预,其中50%需要肠切除。症状持续时间>24小时的患儿比症状<24小时的患儿需要手术(73%对45%;P < 0.001)和肠切除(39%对17%;P = 0.001)的风险更高。14%发现有病理引导点。有2例死亡,19%发生并发症。手术复位后的住院时间为3.9天,但需要肠切除时为6.1天。

结论

空气对比技术可提高肠套叠复位的成功率,且不受先前外部复位失败的影响。就诊延迟会降低放射学复位的成功率,并增加手术干预和肠切除的风险。

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