Holmes Cn, Preko Po, Bolds R, Baidoo J, Jolly Pe
Department of Epidemiology, University of Alabama at Birmingham School of Public Health, 1665 University Boulevard, Birmingham, Alabama, USA.
Ghana Med J. 2008 Mar;42(1):8-15.
Voluntary counselling and testing (VCT) for human immunodeficiency virus (HIV) and treatment of positive pregnant women can reduce mother to child transmission (MTCT) of HIV.
This study was conducted to assess acceptance of HIV VCT and antiretroviral therapy (ART) by pregnant women in Kumasi, Ghana, before and after VCT and ART were available.
Two cross-sectional studies were conducted among women in antenatal clinics. The first, in 2003 among 501 women, before VCT and ART were available in Kumasi. Women who were willing were counselled and tested for HIV. In 2005, after the introduction of VCT and ART by the Ghana Health Service, 675 pregnant women were surveyed regarding HIV/VCT acceptance and uptake.
In 2003, 98% of women accepted counselling and 97% accepted testing; 3.3% tested HIV positive. Multivariate analysis showed that women with secondary education were 88% less likely than those with no/primary education to accept testing (OR=0.12, CI=0.03-0.54,p=0.006). Women who had prior HIV testing were 95% less likely to accept testing (OR=0.05, CI=0.01-0.19, p=0.0001). Women who reported two sexual partners in the past year were 6 times as likely to be HIV positive than those reporting one sexual partner (OR=5.76. CI=1.53 - 21.69, p=>0.05). In 2005, 76% of women reported no prior HIV counselling and 78% no testing.
In 2003, there was wide uptake of VCT by prenatal women. However, in 2005 the majority of pregnant women were not accessing the available VCT services.
摘要 背景:人类免疫缺陷病毒(HIV)自愿咨询检测(VCT)及对HIV阳性孕妇进行治疗可减少HIV母婴传播(MTCT)。
本研究旨在评估在加纳库马西提供VCT和抗逆转录病毒疗法(ART)前后,孕妇对HIV VCT和ART的接受情况。
在产前诊所对女性进行了两项横断面研究。第一项研究于2003年在501名女性中进行,当时库马西尚未提供VCT和ART。愿意接受的女性接受了HIV咨询和检测。2005年,在加纳卫生服务部门引入VCT和ART后,对675名孕妇进行了关于HIV/VCT接受情况和使用情况的调查。
2003年,98%的女性接受了咨询,97%的女性接受了检测;3.3%的检测结果为HIV阳性。多变量分析显示,接受过中等教育的女性接受检测的可能性比未接受教育/接受过小学教育的女性低88%(OR=0.12,CI=0.03-0.54,p=0.006)。之前接受过HIV检测的女性接受检测的可能性低95%(OR=0.05,CI=0.01-0.19,p=0.0001)。报告在过去一年中有两个性伴侣的女性感染HIV的可能性是报告有一个性伴侣的女性的6倍(OR=5.76,CI=1.53-21.69,p=>0.05)。2005年,76%的女性报告之前未接受过HIV咨询,78%的女性报告未接受过检测。
2003年,产前女性对VCT的接受程度较高。然而,2005年大多数孕妇未使用现有的VCT服务。