Jerant Anthony, Moore-Hill Monique, Franks Peter
Department of Family and Community Medicine, University of California Davis School of Medicine, Sacramento, California, USA.
Ann Fam Med. 2009 Jul-Aug;7(4):319-27. doi: 10.1370/afm.996.
Studies suggest peer-led self-management training improves chronic illness outcomes by enhancing illness management self-efficacy. Limitations of most studies, however, include use of multiple outcome measures without predesignated primary outcomes and lack of randomized follow-up beyond 6 months. We conducted a 1-year randomized controlled trial of Homing in on Health (HIOH), a Chronic Disease Self-Management Program variant, addressing these limitations.
We randomized outpatients (N = 415) aged 40 years and older and who had 1 or more of 6 common chronic illnesses, plus functional impairment, to HIOH delivered in homes or by telephone for 6 weeks or to usual care. Primary outcomes were the Medical Outcomes Study 36-ltem short-form health survey's physical component (PCS-36) and mental component (MCS-36) summary scores. Secondary outcomes included the EuroQol EQ-5D and visual analog scale (EQ VAS), hospitalizations, and health care expenditures.
Compared with usual care, HIOH delivered in the home led to significantly higher illness management self-efficacy at 6 weeks (effect size = 0.27; 95% CI, 0.10-0.43) and at 6 months (0.17; 95% CI, 0.01-0.33), but not at 1 year. In-home HIOH had no significant effects on PCS-36 or MCS-36 scores and led to improvement in only 1 secondary outcome, the EQ VAS (1-year effect size = 0.40; CI, 0.14-0.66). HIOH delivered by telephone had no significant effects on any outcomes.
Despite leading to improvements in self-efficacy comparable to those in other CDSMP studies, in-home HIOH had a limited sustained effect on only 1 secondary health status measure and no effect on utilization. These findings question the cost-effectiveness of peer-led illness self-management training from the health system perspective.
研究表明,同伴主导的自我管理培训通过提高疾病管理自我效能来改善慢性病治疗效果。然而,大多数研究的局限性包括使用多种结局指标但未预先指定主要结局,以及缺乏超过6个月的随机随访。我们针对这些局限性开展了一项为期1年的随机对照试验,试验对象为“聚焦健康”(HIOH),这是慢性病自我管理项目的一个变体。
我们将年龄在40岁及以上、患有6种常见慢性病中的1种或多种且伴有功能障碍的门诊患者(N = 415)随机分为两组,一组接受为期6周的居家或电话形式的HIOH干预,另一组接受常规护理。主要结局指标为医学结局研究36项简短健康调查问卷的身体成分(PCS - 36)和精神成分(MCS - 36)汇总得分。次要结局指标包括欧洲五维度健康量表(EuroQol EQ - 5D)和视觉模拟量表(EQ VAS)、住院情况以及医疗保健支出。
与常规护理相比,居家进行的HIOH在6周时(效应量 = 0.27;95%可信区间,0.10 - 0.43)和6个月时(0.17;95%可信区间,0.01 - 0.33)能显著提高疾病管理自我效能,但在1年时未显示出该效果。居家HIOH对PCS - 36或MCS - 36得分无显著影响,仅在1项次要结局指标EQ VAS上有改善(1年效应量 = 0.40;可信区间,0.14 - 0.66)。电话形式的HIOH对任何结局指标均无显著影响。
尽管居家HIOH在提高自我效能方面与其他慢性病自我管理项目研究的效果相当,但仅对1项次要健康状况指标有有限的持续影响,对医疗服务利用无影响。从卫生系统角度来看,这些发现对同伴主导的疾病自我管理培训的成本效益提出了质疑。