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Ensembl 的第十个年头。

Ensembl's 10th year.

机构信息

European Bioinformatics Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1SD, UK.

出版信息

Nucleic Acids Res. 2010 Jan;38(Database issue):D557-62. doi: 10.1093/nar/gkp972. Epub 2009 Nov 11.

Abstract

Ensembl (http://www.ensembl.org) integrates genomic information for a comprehensive set of chordate genomes with a particular focus on resources for human, mouse, rat, zebrafish and other high-value sequenced genomes. We provide complete gene annotations for all supported species in addition to specific resources that target genome variation, function and evolution. Ensembl data is accessible in a variety of formats including via our genome browser, API and BioMart. This year marks the tenth anniversary of Ensembl and in that time the project has grown with advances in genome technology. As of release 56 (September 2009), Ensembl supports 51 species including marmoset, pig, zebra finch, lizard, gorilla and wallaby, which were added in the past year. Major additions and improvements to Ensembl since our previous report include the incorporation of the human GRCh37 assembly, enhanced visualisation and data-mining options for the Ensembl regulatory features and continued development of our software infrastructure.

摘要

Ensembl(http://www.ensembl.org)整合了一套全面的脊索动物基因组的基因组信息,特别侧重于人类、小鼠、大鼠、斑马鱼和其他高价值测序基因组的资源。我们为所有支持的物种提供完整的基因注释,此外还提供针对基因组变异、功能和进化的特定资源。Ensembl 数据以多种格式提供,包括通过我们的基因组浏览器、API 和 BioMart。今年是 Ensembl 成立十周年,在这段时间里,随着基因组技术的进步,该项目也在不断发展壮大。截至第 56 版(2009 年 9 月),Ensembl 支持 51 个物种,包括狨猴、猪、斑马雀、蜥蜴、大猩猩和沙袋鼠,这些物种是在过去一年中添加的。自上次报告以来,Ensembl 的主要新增和改进包括整合了人类 GRCh37 组装、增强了 Ensembl 调控特征的可视化和数据挖掘选项以及继续开发我们的软件基础设施。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4aba/2808936/1a253d6b947e/gkp972f1.jpg

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