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[昆虫抗菌肽:结构、特性与基因调控]

[Insect antimicrobial peptides: structures, properties and gene regulation].

作者信息

Wang Yi-Peng, Lai Ren

机构信息

Kunming Institute of Zoology, the Chinese Academy of Sciences, Kunming 650223, China.

出版信息

Dongwuxue Yanjiu. 2010 Feb;31(1):27-34. doi: 10.3724/sp.j.1141.2010.01027.

Abstract

Insect antimicrobial peptides (AMPs) are an important group of insect innate immunity effectors. Insect AMPs are cationic and contain less than 100 amino acid residues. According to structure, insect AMPs can be divided into a limited number of families. The diverse antimicrobial spectrum of insect AMPs may indicate different modes of action. Research on the model organism Drosophila indicate that insect AMPs gene regulation involves multiple signaling pathways and a large number of signaling molecules.

摘要

昆虫抗菌肽(AMPs)是昆虫先天免疫效应器的重要组成部分。昆虫抗菌肽呈阳离子性,且氨基酸残基少于100个。根据结构,昆虫抗菌肽可分为数量有限的几个家族。昆虫抗菌肽多样的抗菌谱可能表明其作用方式不同。对模式生物果蝇的研究表明,昆虫抗菌肽的基因调控涉及多个信号通路和大量信号分子。

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