Ritter Philip L, Lee Jonathan, Lorig Kate
Stanford Patient Education Research Center, Stanford University, Palo Alto, CA 94304, USA.
Chronic Illn. 2011 Jun;7(2):162-72. doi: 10.1177/1742395311399127. Epub 2011 Feb 28.
The Stanford University Chronic Disease Self-Management Program (CDSMP) has resulted in moderate beneficial outcomes in randomized controlled trials. A study of a modified CDSMP in England suggested that younger participants, those with lower initial self-efficacy and those with greater depression benefited most from the program.
Using data from previous CDSMP programs in English and Spanish, we examined whether there were statistically significant interactions between baseline statuses (demographic, disease and health status variables) and randomization (intervention or usual-care control) in estimating 6-month changes in health status (health distress, activity limitation/role function, self-efficacy and self-reported general health). If an interaction was found, post hoc examinations of the relationships between the baseline variables and outcomes determined the directions of the relationships.
Six moderating variables were found in the original English-language CDSMP and three in the Spanish program. Each moderator was specific to only one outcome within only one of the two studies.
There were no consistent moderating effects across four outcomes and two programs and little evidence to suggest that any groups should be targeted for program recruitment. The CDSMP appears to remain useful to a wide range of people with chronic illness.
斯坦福大学慢性病自我管理项目(CDSMP)在随机对照试验中取得了适度的有益成果。一项针对英国改良版CDSMP的研究表明,年轻参与者、初始自我效能较低者以及抑郁程度较高者从该项目中获益最多。
利用之前英语和西班牙语CDSMP项目的数据,我们研究了在评估健康状况(健康困扰、活动受限/角色功能、自我效能和自我报告的总体健康状况)6个月的变化时,基线状态(人口统计学、疾病和健康状况变量)与随机分组(干预或常规护理对照)之间是否存在统计学上的显著交互作用。如果发现存在交互作用,则对基线变量与结果之间的关系进行事后检验,以确定关系的方向。
在最初的英语CDSMP中发现了六个调节变量,在西班牙语项目中发现了三个。每个调节变量仅特定于两项研究之一中的一个结果。
在四个结果和两个项目中没有一致的调节效应,几乎没有证据表明应该针对任何群体进行项目招募。CDSMP似乎对广泛的慢性病患者仍然有用。