Department of Nutrition and Food Hygiene, School of Public Health, Peking University Health Science Center, Beijing, China.
J Atheroscler Thromb. 2012;19(2):159-68. doi: 10.5551/jat.10116. Epub 2011 Nov 1.
The present study aimed to determine the up-to-date prevalence, awareness, treatment, and control of dyslipidemia, and their distribution and related influencing factors in adults in Beijing, China.
A cross-sectional study was conducted in 2008, using a four-stratified cluster sampling. Data from a questionnaire, physical examination, and blood sampling were obtained from 5761 adults aged 18-79 years.
The prevalence of high TC, high LDL-C, low HDL-C and TG was 12.2%, 17.9%, 12.0% and 15.1%, respectively. The prevalence of dyslipidemia was 35.4% (42.9% in men and 30.1% in women), and was similar in rural (35.3%) and urban (35.8%) areas. Dyslipidemia was associated with male gender, age, a family history of dyslipidemia, education at college or above, current smoker, overweight and obesity, intermediate and high waist circumference, hypertension and diabetes. Among all participants with dyslipidemia, 22.2% were aware of the diagnosis, 10.2% were receiving treatment, and 3.8% had dyslipidemia controlled. The proportion of those aware of their condition and those who were treated increased with age in both sexes. Of those aware of their dyslipidemia, 46.1% were on treatment, 51.0% had modified their lifestyle, and 24.5% were not receiving treatment or modifying their lifestyle.
The major type of dyslipidemia in Beijing is high LDL-C rather than high TG. The prevalence of dyslipidemia is similarly high in rural and urban areas, with low awareness, treatment and control. A comprehensive strategy toward the prevention, screening, treatment, and control of dyslipidemia is needed to slow the epidemic of cardiovascular disease.
本研究旨在确定北京市成年人血脂异常的最新患病率、知晓率、治疗率和控制率及其分布情况和相关影响因素。
采用四阶段分层整群抽样方法,于 2008 年进行横断面研究。共纳入 5761 名 18-79 岁成年人,收集问卷调查、体格检查和血样检测数据。
高 TC、高 LDL-C、低 HDL-C 和高 TG 的患病率分别为 12.2%、17.9%、12.0%和 15.1%。血脂异常的患病率为 35.4%(男性为 42.9%,女性为 30.1%),城乡患病率相似(农村为 35.3%,城市为 35.8%)。血脂异常与男性、年龄、血脂异常家族史、大学及以上文化程度、当前吸烟者、超重和肥胖、中/高腰围、高血压和糖尿病有关。在所有血脂异常患者中,22.2%知晓诊断,10.2%接受治疗,3.8%血脂异常得到控制。无论男女,知晓率和治疗率均随年龄增长而增加。在知晓自身血脂异常的人群中,46.1%接受治疗,51.0%改善了生活方式,24.5%未接受治疗或未改善生活方式。
北京市成年人血脂异常的主要类型是高 LDL-C,而非高 TG。城乡血脂异常患病率均较高,知晓率、治疗率和控制率均较低。需要采取综合策略来预防、筛查、治疗和控制血脂异常,以减缓心血管疾病的流行。