Roqué i Figuls Marta, Giné-Garriga Maria, Granados Rugeles Claudia, Perrotta Carla
Iberoamerican Cochrane Centre, Institute of Biomedical Research (IIB Sant Pau), Barcelona, CIBER Epidemiología y Salud Pública(CIBERESP), Spain, Barcelona, Spain.
Cochrane Database Syst Rev. 2012 Feb 15(2):CD004873. doi: 10.1002/14651858.CD004873.pub4.
This is an update of the original Cochrane review published in 2005 and updated in 2007. Acute bronchiolitis is the leading cause of medical emergencies during winter in children younger than two years of age. Chest physiotherapy is thought to assist infants in the clearance of secretions and to decrease ventilatory effort.
The main objective was to determine the efficacy of chest physiotherapy in infants aged less than 24 months old with acute bronchiolitis. A secondary objective was to determine the efficacy of different techniques of chest physiotherapy (for example, vibration and percussion and passive forced exhalation).
We searched the Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library 2011, Issue 4) which contains the Cochrane Acute Respiratory Infections Group's Specialised Register, MEDLINE (1966 to November week 3, 2011), MEDLINE in-process and other non-indexed citations (8 December 2011), EMBASE.com (1990 to December 2011), CINAHL (1982 to December 2011), LILACS (1985 to December 2011) and Web of Science (1985 to December 2011).
Randomised controlled trials (RCTs) in which chest physiotherapy was compared against no intervention or against another type of physiotherapy in bronchiolitis patients younger than 24 months of age.
Two review authors independently extracted data. Primary outcomes were respiratory parameters and improvement in severity of disease. Secondary outcomes were length of hospital stay, duration of oxygen supplementation and the use of bronchodilators and steroids. No pooling of data was possible.
Nine clinical trials including 891 participants were included comparing physiotherapy with no intervention. Five trials (246 participants) evaluated vibration and percussion techniques and four trials (645 participants) evaluated passive expiratory techniques. We observed no significant differences in the severity of disease (eight trials, 867 participants). Results were negative for both types of physiotherapy. We observed no differences between groups in respiratory parameters (two trials, 118 participants), oxygen requirements (one trial, 50 participants), length of stay (five trials, 222 participants) or severe side effects (two trials, 595 participants). Differences in mild transient adverse effects (vomiting and respiratory instability) have been observed (one trial, 496 participants).
AUTHORS' CONCLUSIONS: Since the last publication of this review new good-quality evidence has appeared, strengthening the conclusions of the review. Chest physiotherapy does not improve the severity of the disease, respiratory parameters, or reduce length of hospital stay or oxygen requirements in hospitalised infants with acute bronchiolitis not on mechanical ventilation. Chest physiotherapy modalities (vibration and percussion or forced expiratory techniques) have shown equally negative results.
这是对2005年发表并于2007年更新的原始Cochrane系统评价的更新。急性细支气管炎是两岁以下儿童冬季医疗急症的主要原因。胸部物理治疗被认为有助于婴儿清除分泌物并减少呼吸用力。
主要目的是确定胸部物理治疗对24个月以下急性细支气管炎婴儿的疗效。次要目的是确定不同胸部物理治疗技术(如振动、叩击和被动强制呼气)的疗效。
我们检索了Cochrane对照试验中心注册库(CENTRAL)(《Cochrane图书馆》2011年第4期),其中包含Cochrane急性呼吸道感染小组的专业注册库、MEDLINE(1966年至2011年11月第3周)、MEDLINE在研及其他未索引文献(2011年12月8日)、EMBASE.com(1990年至2011年12月)、CINAHL(1982年至2011年12月)、LILACS(1985年至2011年12月)和科学引文索引(1985年至2011年12月)。
将胸部物理治疗与不干预或与另一种物理治疗方法进行比较的随机对照试验(RCT),受试对象为24个月以下的细支气管炎患者。
两名综述作者独立提取数据。主要结局为呼吸参数和疾病严重程度的改善情况。次要结局为住院时间、吸氧时间以及支气管扩张剂和类固醇的使用情况。无法进行数据合并。
纳入了9项临床试验,共891名受试者,比较了物理治疗与不干预的效果。5项试验(246名受试者)评估了振动和叩击技术,4项试验(645名受试者)评估了被动呼气技术。我们观察到疾病严重程度无显著差异(8项试验,867名受试者)。两种物理治疗方法的结果均为阴性。我们观察到两组在呼吸参数(2项试验,118名受试者)、吸氧需求(1项试验,50名受试者)、住院时间(5项试验,222名受试者)或严重副作用(2项试验,595名受试者)方面无差异。观察到在轻微短暂不良反应(呕吐和呼吸不稳定)方面存在差异(1项试验,496名受试者)。
自本综述上次发表以来,出现了新的高质量证据,强化了本综述的结论。胸部物理治疗并不能改善非机械通气的住院急性细支气管炎婴儿的疾病严重程度、呼吸参数,也不能缩短住院时间或减少吸氧需求。胸部物理治疗方式(振动和叩击或强制呼气技术)均显示出同样阴性的结果。