Kessler Ronald C, Avenevoli Shelli, Costello Jane, Green Jennifer Greif, Gruber Michael J, McLaughlin Katie A, Petukhova Maria, Sampson Nancy A, Zaslavsky Alan M, Merikangas Kathleen Ries
Department of Health Care Policy, Harvard Medical School, Boston, MA 02115, USA.
Arch Gen Psychiatry. 2012 Apr;69(4):381-9. doi: 10.1001/archgenpsychiatry.2011.1603.
Estimates of DSM-IV disorder prevalence are high; stringent criteria to define need for services are desired.
To present US national data on the prevalence and sociodemographic correlates of 12-month serious emotional disturbance (SED), defined by the US Substance Abuse and Mental Health Services Administration, from the National Comorbidity Survey Replication Adolescent Supplement.
The National Comorbidity Survey Replication Adolescent Supplement is a national survey of DSM-IV anxiety, mood, behavior, and substance disorders among US adolescents.
Dual-frame household and school samples of US adolescents.
Total of 6483 pairs of adolescents aged 13 to 17 (interviews) and parents (questionnaires).
The DSM-IV disorders were assessed with the World Health Organization Composite International Diagnostic Interview and validated with blinded clinical interviews based on the Schedule for Affective Disorders and Schizophrenia for School-Age Children. Serious emotional disturbance was operationalized as a DSM-IV/Composite International Diagnostic Interview disorder with a score of 50 or less on the Children's Global Assessment Scale (ie, moderate impairment in most areas of functioning or severe impairment in at least 1 area). Concordance of Composite International Diagnostic Interview SED diagnoses with blinded Schedule for Affective Disorders and Schizophrenia for School-Age Children diagnoses was good.
The estimated prevalence of SED was 8.0%. Most SEDs were due to behavior (54.5%) or mood (31.4%) disorders. Although respondents with 3 or more disorders made up only 29.0% of those with 12-month DSM-IV/Composite International Diagnostic Interview disorders, they constituted 63.5% of SEDs. Predictive effects of high comorbidity were significantly greater than the product of their disorder-specific odds ratios and consistent across disorder types. Associations of sociodemographic variables with SED were generally nonsignificant after controlling for disorder type and number.
The high estimated 12-month prevalence of DSM-IV disorders among US adolescents is largely due to mild cases. The significant between-disorder differences in risk of SED and the significant effect of high comorbidity have important public health implications for targeting interventions.
《精神疾病诊断与统计手册》第四版(DSM-IV)中对精神障碍患病率的估计值较高;因此需要严格的标准来界定服务需求。
通过《国家共病调查复制版青少年补充调查》,呈现美国国家药物滥用和精神健康服务管理局所定义的12个月严重情绪障碍(SED)的患病率及社会人口学相关因素的数据。
《国家共病调查复制版青少年补充调查》是一项针对美国青少年的DSM-IV焦虑、情绪、行为和物质使用障碍的全国性调查。
美国青少年的双框架家庭和学校样本。
共有6483对年龄在13至17岁的青少年(访谈)及其父母(问卷调查)。
采用世界卫生组织综合国际诊断访谈评估DSM-IV障碍,并根据学龄儿童情感障碍和精神分裂症量表通过盲法临床访谈进行验证。严重情绪障碍被定义为DSM-IV/综合国际诊断访谈障碍,且儿童总体评估量表得分在50分及以下(即大多数功能领域存在中度损害或至少一个领域存在严重损害)。综合国际诊断访谈中SED诊断与盲法学龄儿童情感障碍和精神分裂症量表诊断的一致性良好。
SED的估计患病率为8.0%。大多数SED是由行为障碍(54.5%)或情绪障碍(31.4%)引起的。虽然患有3种或更多障碍的受访者仅占12个月内患有DSM-IV/综合国际诊断访谈障碍者的29.0%,但他们却占SED患者的63.5%。高共病的预测效应显著大于其特定障碍比值比的乘积,且在不同障碍类型中一致。在控制了障碍类型和数量后,社会人口学变量与SED的关联通常不显著。
美国青少年中DSM-IV障碍12个月患病率估计值较高主要归因于轻症病例。SED风险在不同障碍之间存在显著差异,且高共病具有显著影响,这对干预措施的针对性具有重要的公共卫生意义。