儿童尿路结石：医学处理方法。
Urolithiasis in children: medical approach.
机构信息
Division of Nephrology, Department of Pediatrics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
出版信息
Pediatr Clin North Am. 2012 Aug;59(4):881-96. doi: 10.1016/j.pcl.2012.05.009. Epub 2012 Jun 15.
Abstract
Childhood urolithiasis is an evolving condition with an increasing incidence and prevalence over the last 2 decades. Over that time the underlying cause has shifted from predominantly infectious to metabolic in nature. This review describes the pathophysiology, underlying metabolic abnormalities, clinical presentation, evaluation, and management of childhood urolithiasis. A comprehensive metabolic evaluation is essential for all children with renal calculi, given the high rate of recurrence and the importance of excluding inherited progressive conditions.
摘要
儿童尿石症是一种不断发展的疾病，在过去 20 年中其发病率和患病率都在不断上升。在此期间，其根本病因已从主要的感染性转变为以代谢性为主。本文综述了儿童尿石症的病理生理学、潜在代谢异常、临床表现、评估和治疗。鉴于高复发率和排除遗传性进行性疾病的重要性，对于所有肾结石儿童，都需要进行全面的代谢评估。
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