加巴喷丁治疗晚期恶性肿瘤患者的持续性呃逆
Gabapentin in the treatment of persistent hiccups in advanced malignancy.
作者信息
Menon Mahesh
机构信息
Department of Pain Medicine and Palliative Care Services, Kokilaben Dhirubhai Ambani Hospital, Four bungalows, Andheri (West), Mumbai-53, India.
出版信息
Indian J Palliat Care. 2012 May;18(2):138-40. doi: 10.4103/0973-1075.100839.
Hiccups are a distressing symptom in advanced malignancies in the setting of palliative care. A case of persistent hiccups treated with oral Gabapentin is presented to highlight the clinical and ethical dilemmas in patients with advanced malignancy. A 70-year-old male with non-small cell cancer of the lung with widespread metastases presented with persistent hiccups. The patient and family sought only symptom relief from home, without hospitalization or further investigations. The hiccups were dramatically relieved by oral Gabapentin, highlighting the recent reports that mention this molecule as being useful for hiccups. Gabapentin is a simple tool that may be utilized by palliative care physicians to relieve hiccups in advanced malignancies.
在姑息治疗背景下，呃逆是晚期恶性肿瘤患者令人苦恼的症状。本文介绍一例口服加巴喷丁治疗持续性呃逆的病例，以突出晚期恶性肿瘤患者面临的临床和伦理困境。一名70岁男性，患有广泛转移的非小细胞肺癌，出现持续性呃逆。患者及其家属仅希望在家中缓解症状，未住院或进一步检查。口服加巴喷丁后呃逆明显缓解，这凸显了近期一些报道中提到该药物对呃逆有用。加巴喷丁是一种简单的工具，姑息治疗医生可利用它来缓解晚期恶性肿瘤患者的呃逆症状。
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