运动对癌症患者治疗期间肌肉质量和力量的影响——系统评价。
Effect of physical exercise on muscle mass and strength in cancer patients during treatment--a systematic review.
机构信息
European Palliative Care Research Centre, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway; Department of Neuroscience, Faculty of Medicine, Norwegian University of Science and Technology (NTNU), Trondheim, Norway; Cancer Clinic, St. Olavs Hospital, Trondheim University Hospital, Trondheim, Norway.
出版信息
Crit Rev Oncol Hematol. 2013 Dec;88(3):573-93. doi: 10.1016/j.critrevonc.2013.07.001. Epub 2013 Aug 9.
Cancer treatment and its side effects may cause muscle wasting. Physical exercise has the potential to increase muscle mass and strength and to improve physical function in cancer patients undergoing treatment. A systematic review was conducted to study the effect of physical exercise (aerobic, resistance or a combination of both) on muscle mass and strength in cancer patients with different type and stage of cancer disease. Electronic searches were performed up to January 11th 2012, identifying 16 randomised controlled trials for final data synthesis. The studies demonstrated that aerobic and resistance exercise improves upper and lower body muscle strength more than usual care. Few studies have assessed the effect of exercise on muscle mass. Most studies were performed in patients with early stage breast or prostate cancer. Evidence on the effect of physical exercise on muscle strength and mass in cancer patients with advanced disease is lacking. More exercise studies in patients with advanced cancer and at risk of cancer cachexia are warranted.
癌症治疗及其副作用可能导致肌肉减少。身体锻炼有可能增加肌肉质量和力量，并改善正在接受治疗的癌症患者的身体功能。进行了系统评价，以研究身体锻炼（有氧、抗阻或两者结合）对不同类型和不同癌症阶段的癌症患者的肌肉质量和力量的影响。电子检索截止到 2012 年 1 月 11 日，最终综合了 16 项随机对照试验的数据。研究表明，有氧和抗阻运动比常规治疗更能改善上下肢肌肉力量。很少有研究评估运动对肌肉质量的影响。大多数研究都在早期乳腺癌或前列腺癌患者中进行。关于身体锻炼对晚期癌症患者肌肉力量和质量影响的证据不足。需要在晚期癌症和有癌症恶病质风险的患者中开展更多的运动研究。
Zotero 插件