Amel Ivan Erli, A Mangaiarkkarasi
Associate Professor, Department of Pathology, Sri Manakula Vinyagar Medical College Hospital , Pondicherry - 605107, India .
Associate Professor, Department of Pharmacology, Sri Manakula Vinyagar Medical College Hospital , Pondicherry - 605107, India .
J Clin Diagn Res. 2013 Nov;7(11):2487-90. doi: 10.7860/JCDR/2013/6370.3586. Epub 2013 Oct 25.
Anaemia occurring during pregnancy is an important public health problem in developing countries. In India, anaemia is one of the most common causes of maternal death, accounting for 20% of total maternal deaths. This study was conducted with the aim of evaluating anaemia among booked antenatal mothers during the last trimester, its possible impact on pregnancy and its outcome in antenatal mothers, visiting antenatal clinic in a teaching tertiary care hospital at Pondicherry, India.
This hospital based, descriptive, cross sectional study was conducted in the Department of Clinical Pathology and Pharmacology at Sri Manakula Vinayagar Medical College Hospital in Pondicherry, India. Socio-economic and gestational status data was collected with the help of structured questionnaire from booked antenatal mothers in third trimester. Venous blood was collected for the estimation of Haemoglobin by using Sahli's Haemoglobinometer and morphological typing of anaemia was estimated by using Leishmann Stain peripheral blood smears. The women were followed-up till delivery and their antenatal, neonatal and other birth outcomes were recorded.
Seventy five booked antenatal women, aged 19 - 40 years, with gestational ages of 27- 40 weeks, were recruited for the study. We observed that among 75 antenatal mothers, the Haemoglobin level was less than 10grams% in 83% cases and that it was more than 10 grams% in 17% cases. Iron deficiency anaemia and dimorphic anaemia were recorded in 37% and 19% of the women respectively. High percentage of anaemia was noted in women of higher age group (23-27 years), in those with multi-parity (55%) and low educational levels (100%) and in mothers of low socio-economic status (100%). In the pregnancy outcomes, 85% and 60% anaemic mothers reported maternal and foetal complications respectively.
In spite of regular antenatal visits in third trimester, maternal anaemia is still high and it is often associated with low education status, socio-economic status and multi-parity, based on our study. There is a need of health education programmes with respect to haematinics compliance and adequate intake of iron rich diet during pregnancy, to be strengthened for safe maternal and foetal outcomes.
孕期贫血是发展中国家一个重要的公共卫生问题。在印度,贫血是孕产妇死亡的最常见原因之一,占孕产妇死亡总数的20%。本研究旨在评估印度本地治里一家教学三级护理医院产前门诊中已登记的孕晚期母亲的贫血情况、其对妊娠的可能影响及其妊娠结局。
本研究为基于医院的描述性横断面研究,在印度本地治里市斯里马纳库拉·维奈亚加尔医学院医院临床病理与药理学系开展。借助结构化问卷,收集孕晚期已登记的产前母亲的社会经济和妊娠状况数据。采集静脉血,使用萨利血红蛋白计测定血红蛋白,并使用瑞氏染色外周血涂片评估贫血的形态学类型。对这些女性进行随访直至分娩,并记录她们的产前、新生儿及其他出生结局。
招募了75名年龄在19至40岁、孕周为27至40周的已登记产前女性参与本研究。我们观察到,在75名产前母亲中,83%的病例血红蛋白水平低于10克%,17%的病例血红蛋白水平高于10克%。分别有37%和19%的女性被诊断为缺铁性贫血和双相性贫血。在年龄较大的年龄组(23至27岁)、多产次女性(55%)、低教育水平女性(100%)以及社会经济地位较低的母亲(100%)中,贫血比例较高。在妊娠结局方面,分别有85%和60%的贫血母亲报告出现了母体和胎儿并发症。
根据我们的研究,尽管在孕晚期进行了定期产前检查,但孕产妇贫血率仍然很高,且往往与低教育水平、社会经济地位和多产次有关。需要加强关于孕期补血剂依从性和充足摄入富含铁的饮食的健康教育项目,以实现安全的母婴结局。