基于新型 BODIPY 的荧光比率型传感器用于检测 Fe3+及其在活细胞中的生物成像应用。
Novel BODIPY-based fluorescence turn-on sensor for Fe3+ and its bioimaging application in living cells.
机构信息
Department of Chemistry and ‡CREOL, The College of Optics and Photonics, University of Central Florida , Orlando, Florida 32816, United States.
出版信息
ACS Appl Mater Interfaces. 2014;6(21):18408-12. doi: 10.1021/am506262u. Epub 2014 Oct 22.
A novel boron-dipyrromethene (BODIPY) based fluorescence turn-on sensor for detecting Fe(3+) in aqueous media is reported with 23-fold fluorescence enhancement. The sensor is comprised of a combination of BODIPY fluorophore and a new Fe(3+)-recognizing cryptand that exhibits high selectivity, sensitivity, and reversibility toward Fe(3+) detection. Cell imaging studies demonstrate that this sensor is capable of sensing Fe(3+) in living cells.
本文报道了一种新型的基于硼二吡咯亚甲基（BODIPY）的荧光开启传感器，用于检测水相介质中的 Fe(3+)，具有 23 倍的荧光增强。该传感器由 BODIPY 荧光团和一种新的 Fe(3+)识别cryptand 组成，对 Fe(3+)检测表现出高选择性、高灵敏度和高可逆性。细胞成像研究表明，该传感器能够在活细胞中检测 Fe(3+)。
Zotero 插件