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地中海地区巴利阿里群岛青少年血脂异常及相关危险因素的患病率

Prevalence of dyslipidaemia and associated risk factors among Balearic Islands adolescents, a Mediterranean region.

作者信息

Bibiloni M M, Salas R, Pons A, Tur J A

机构信息

Research Group on Community Nutrition and Oxidative Stress, University of Balearic Islands, IdISPa, and CIBERobn (Physiopathology of Obesity and Nutrition CB12/03/30038), Palma de Mallorca, Spain.

Faculty of Public Health Nutrition, Autonomous University of Nuevo León, Monterrey, Mexico.

出版信息

Eur J Clin Nutr. 2015 Jun;69(6):722-8. doi: 10.1038/ejcn.2014.236. Epub 2014 Oct 29.

Abstract

BACKGROUND/OBJECTIVES: The increase in overweight and obese children and adolescents may be linked to increased rates of dyslipidaemia. The aim was to assess the prevalence of dyslipidaemia and associated risk factors among the Balearic Islands' adolescent population.

SUBJECTS/METHODS: A random sample (n=362, 143 boys and 219 girls, aged 12-17 years) was interviewed, anthropometrically measured and fasting blood samples taken. According to the 2011 Expert Panel on Integrated Guidelines for Cardiovascular Health and Risk Reduction in Children and Adolescents, dyslipidaemia was defined as the presence of one or more of the following levels (mg/dl): total cholesterol (TChol)⩾200, low-density lipoprotein cholesterol (LDL-chol)⩾130, non-high-density lipoprotein cholesterol (non-HDL-chol)⩾145, high-density lipoprotein cholesterol (HDL-chol)<40 and tryglicerides (TG)⩾130.

RESULTS

The overall prevalence of borderline-high+high TChol, LDL-chol, non-HDL-chol and TG was 24.3, 10.4, 13.3 and 14.9%, respectively. The TChol prevalence was higher among girls (27.8%) than the boys (19.1%). The overall prevalence of borderline-low+low HDL-chol was 12.2% (boys 20.7%; girls 6.3%). The overall prevalence of dyslipidaemia was 13.7% (boys 14.9%; girls 12.9%). Low HDL-chol levels were the most prevalent dyslipidaemia in boys (6.4%) and high TChol in girls (9.1%). Overweight/obese subjects were more likely to have at least one abnormal lipid concentration (odds ratio (OR): 2.10; 95% confidence interval (CI): 1.06-4.15) and subjects with abdominal obesity were more likely to have at least one abnormal lipid level (OR: 3.17; 95% CI: 1.04-9.66).

CONCLUSIONS

One in ten Balearic Islands' adolescents has at least one abnormal lipid concentration. Body mass index status and waist-to-height ratio were associated with the prevalence of at least one abnormal lipid level.

摘要

背景/目的:超重和肥胖儿童及青少年人数的增加可能与血脂异常率上升有关。本研究旨在评估巴利阿里群岛青少年人群中血脂异常的患病率及相关危险因素。

对象/方法:选取一个随机样本(n = 362,143名男孩和219名女孩,年龄12 - 17岁)进行访谈、人体测量并采集空腹血样。根据2011年儿童和青少年心血管健康与风险降低综合指南专家小组的标准,血脂异常定义为存在以下一种或多种水平(mg/dl):总胆固醇(TChol)⩾200、低密度脂蛋白胆固醇(LDL-chol)⩾130、非高密度脂蛋白胆固醇(non-HDL-chol)⩾145、高密度脂蛋白胆固醇(HDL-chol)<40以及甘油三酯(TG)⩾130。

结果

临界高+高TChol、LDL-chol、non-HDL-chol和TG的总体患病率分别为24.3%、10.4%、13.3%和14.9%。女孩的TChol患病率(27.8%)高于男孩(19.1%)。临界低+低HDL-chol的总体患病率为12.2%(男孩20.7%;女孩6.3%)。血脂异常的总体患病率为13.7%(男孩14.9%;女孩12.9%)。HDL-chol水平低是男孩中最常见的血脂异常类型(6.4%),而TChol高是女孩中最常见的血脂异常类型(9.1%)。超重/肥胖受试者更有可能至少有一项血脂浓度异常(比值比(OR):2.10;95%置信区间(CI):1.06 - 4.15),腹部肥胖的受试者更有可能至少有一项血脂水平异常(OR:3.17;95% CI:1.04 - 9.66)。

结论

巴利阿里群岛每十名青少年中就有一人至少有一项血脂浓度异常。体重指数状况和腰高比与至少一项血脂水平异常的患病率相关。

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