Wade Shari L, Taylor H Gerry, Cassedy Amy, Zhang Nanhua, Kirkwood Michael W, Brown Tanya M, Stancin Terry
1 Division of Physical Medicine and Rehabilitation, Department of Pediatrics, Cincinnati Children's Hospital Medical Center and University of Cincinnati College of Medicine , Cincinnati, Ohio.
2 Division of Developmental and Behavioral Pediatrics and Psychology, Department of Pediatrics, Case Western Reserve University and Rainbow Babies and Children's Hospital , University Hospitals Case Medical Center, Cleveland, Ohio.
J Neurotrauma. 2015 Jul 1;32(13):967-75. doi: 10.1089/neu.2014.3684. Epub 2015 May 7.
Family problem-solving therapy (FPST) has been shown to reduce behavior problems after pediatric traumatic brain injury (TBI). It is unclear whether treatment gains are maintained. We sought to evaluate the maintenance of improvements in behavior problems after a Web-based counselor-assisted FPST (CAPS) intervention compared to an Internet resource comparison (IRC) intervention provided to adolescents within the initial year post-TBI. We hypothesized that family socioeconomic status, child educational status, and baseline levels of symptoms would moderate the efficacy of the treatment over time. Participants included 132 adolescents ages 12-17 years who sustained a complicated mild-to-severe TBI 1-6 months before study enrollment. Primary outcomes were the Child Behavior Checklist Internalizing and Externalizing Totals. Mixed-models analyses, using random intercepts and slopes, were conducted to examine group differences over time. There was a significant group×time×grade interaction (F(1,304)=4.42; p=0.03) for internalizing problems, with high school-age participants in CAPS reporting significantly lower symptoms at 18 months postbaseline than those in the IRC. Post-hoc analyses to elucidate the nature of effects on internalizing problems revealed significant group×time×grade interactions for the anxious/depressed (p=0.03) and somatic complaints subscales (p=0.04). Results also indicated significant improvement over time for CAPS participants who reported elevated externalizing behavior problems at baseline (F(1, 310)=7.17; p=0.008). Findings suggest that CAPS may lead to long-term improvements in behavior problems among older adolescents and those with pretreatment symptoms.
家庭问题解决疗法(FPST)已被证明可减少小儿创伤性脑损伤(TBI)后的行为问题。目前尚不清楚治疗效果能否维持。我们试图评估与为TBI后首年的青少年提供的互联网资源对照(IRC)干预相比,基于网络的咨询师辅助家庭问题解决疗法(CAPS)干预后行为问题改善情况的维持情况。我们假设家庭社会经济地位、儿童教育状况和症状基线水平会随着时间推移调节治疗效果。参与者包括132名年龄在12 - 17岁的青少年,他们在研究入组前1 - 6个月遭受了复杂的轻度至重度TBI。主要结局指标是儿童行为量表内化和外化总分。采用随机截距和斜率进行混合模型分析,以检验随时间的组间差异。在内化问题方面存在显著的组×时间×年级交互作用(F(1,304)=4.42;p = 0.03),CAPS组中高中年龄的参与者在基线后18个月报告的症状显著低于IRC组。为阐明对内化问题影响性质的事后分析显示,在焦虑/抑郁(p = 0.03)和躯体主诉分量表(p = 0.04)方面存在显著的组×时间×年级交互作用。结果还表明,基线时报告外化行为问题升高的CAPS参与者随时间有显著改善(F(1, 310)=7.17;p = 0.008)。研究结果表明,CAPS可能会使年龄较大的青少年以及有治疗前症状的青少年的行为问题得到长期改善。