Fernández-Suárez Elena, Villa-Estébanez Rubén, Garcia-Martinez Alberto, Fidalgo-González José A, Zanabili Al-Sibbai Ahmad A, Salas-Puig Javier
Hospital Universitario Central de Asturias, 33006 Oviedo, Espana.
Rev Neurol. 2015 Jun 16;60(12):535-42.
Epilepsy is a disease with great social and economic impact. The prevalence should be used as the most important basis for planning the secondary and tertiary prevention.
To identify patients with a diagnosis of epilepsy in a primary care center and determine the prevalence, demographic characteristics, type of epileptic syndrome and the use of antiepileptic drugs.
Retrospective cross-sectional descriptive study. Included 196 patients with a diagnosis of epilepsy belonging to a primary care center and review the medical history, studying socio-demographic variables and clinical-pharmacological.
The prevalence of epilepsy: 8.4/1000 inhabitants. Mean age: 50.3 years. Sex: 52.6% men.
79.6% urban. Family history of epilepsy: 14.8%. Type of epilepsy: symptomatic focal stroke (14.3%), idiopathic generalized (13.8%), focal cryptogenic (8.7%), not classified (31.1%). Average age at the beginning of seizures: 31.6 years. Neurological and/or psychiatric comorbidity: 62.8%. Last follow-up: 18.9% without antiepileptic treatment, 56.6% monotherapy and 24.5% polytherapy. Seizure-free: 76.5%. Drugs most frequently prescribed: valproic acid, carbamazepine, phenytoin, lamotrigine, levetiracetam. 78.6% without side effects. Exitus: 4.1%.
The prevalence of patients with epilepsy was 8.4/1000 inhabitants, most frequent etiology the symptomatic focal stroke. More than half of patients suffered neurological and/or psychiatric comorbidity. At the end of follow-up the great majority were seizure-free without adverse effects of the antiepileptic drug treatment.
癫痫是一种具有重大社会和经济影响的疾病。患病率应用作二级和三级预防规划的最重要依据。
在初级保健中心识别癫痫诊断患者,并确定患病率、人口统计学特征、癫痫综合征类型及抗癫痫药物的使用情况。
回顾性横断面描述性研究。纳入了196例来自初级保健中心的癫痫诊断患者,回顾病史,研究社会人口统计学变量及临床药理学情况。
癫痫患病率:8.4/1000居民。平均年龄:50.3岁。性别:男性占52.6%。
79.6%为城市居民。癫痫家族史:14.8%。癫痫类型:症状性局灶性卒中(14.3%)、特发性全身性癫痫(13.8%)、局灶性隐源性癫痫(8.7%)、未分类(31.1%)。癫痫发作起始的平均年龄:31.6岁。神经和/或精神合并症:62.8%。末次随访:18.9%未接受抗癫痫治疗,56.6%接受单药治疗,24.5%接受联合治疗。无癫痫发作:76.5%。最常处方的药物:丙戊酸、卡马西平、苯妥英、拉莫三嗪、左乙拉西坦。78.6%无副作用。死亡:4.1%。
癫痫患者的患病率为8.4/1000居民,最常见病因是症状性局灶性卒中。超过一半的患者患有神经和/或精神合并症。随访结束时,绝大多数患者无癫痫发作,且抗癫痫药物治疗无不良反应。