RWTH Aachen University, Helmholtz Institute for Biomedical Engineering, Biointerface Laboratory, Aachen, Germany.
Klinikum Coburg, III. Medizinische Klinik, Coburg, Germany.
Clin Kidney J. 2012 Feb;5(Suppl 1):i3-i14. doi: 10.1093/ndtplus/sfr163.
As a cofactor in numerous enzymatic reactions, magnesium fulfils various intracellular physiological functions. Thus, imbalance in magnesium status-primarily hypomagnesaemia as it is seen more often than hypermagnesaemia-might result in unwanted neuromuscular, cardiac or nervous disorders. Measuring total serum magnesium is a feasible and affordable way to monitor changes in magnesium status, although it does not necessarily reflect total body magnesium content. The following review focuses on the natural occurrence of magnesium and its physiological function. The absorption and excretion of magnesium as well as hypo- and hypermagnesaemia will be addressed.
作为许多酶反应的辅助因子,镁在细胞内发挥多种生理功能。因此,镁平衡状态的改变——主要是低镁血症,因为它比高镁血症更常见——可能导致不需要的神经肌肉、心脏或神经紊乱。测量血清总镁是监测镁平衡变化的一种可行且经济的方法,尽管它不一定反映体内镁的总含量。以下综述重点介绍镁的自然发生及其生理功能。还将讨论镁的吸收和排泄以及低镁血症和高镁血症。