生物膜通过基质蛋白水解招募霍乱弧菌。

Biofilm recruitment of Vibrio cholerae by matrix proteolysis.

机构信息

Department of Molecular Biology and The Laboratory for Molecular Infection Medicine Sweden (MIMS), Umeå University, SE-90187 Umeå, Sweden.

出版信息

Trends Microbiol. 2015 Nov;23(11):667-668. doi: 10.1016/j.tim.2015.09.004. Epub 2015 Oct 1.

DOI:10.1016/j.tim.2015.09.004

PMID:26439292

Abstract

The appearance of bacterial biofilms involves secretion of polysaccharides and proteins that form an extracellular matrix embedding the bacteria. Proteases have also been observed, but their role has remained unclear. Smith and co-workers have now found that proteolysis can contribute to further recruitment of bacteria to Vibrio cholerae biofilms.

摘要

细菌生物膜的形成涉及多糖和蛋白质的分泌，这些物质形成了嵌入细菌的细胞外基质。也观察到了蛋白酶，但它们的作用仍不清楚。Smith 及其同事现在发现，蛋白水解作用可以促进更多的细菌被招募到霍乱弧菌生物膜中。