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1型糖尿病的减肥手术:一项系统评价

Bariatric Surgery in Type 1 Diabetes Mellitus: A Systematic Review.

作者信息

Mahawar Kamal K, De Alwis Nimantha, Carr William R J, Jennings Neil, Schroeder Norbert, Small Peter K

机构信息

Bariatric Unit, Sunderland Royal Hospital, Sunderland, SR4 7TP, UK.

出版信息

Obes Surg. 2016 Jan;26(1):196-204. doi: 10.1007/s11695-015-1924-z.

Abstract

Bariatric surgery is recognised as an effective treatment strategy for obese patients with type 2 diabetes mellitus. An increasing number of patients with type 1 diabetes mellitus also suffer with obesity and obesity-associated comorbidities but the role of bariatric and metabolic surgery in this group of patients is unclear. This systematic review investigates published English language scientific literature to understand the results of bariatric surgery in obese patients with type 1 diabetes mellitus. We found that these patients can experience significant weight loss and comorbidity resolution with bariatric surgery. Though most patients also see a decline in total insulin requirement, glycaemic control remains difficult. Most of the patients reported in literature have undergone gastric bypass but data is insufficient to recommend any particular procedure.

摘要

减重手术被认为是治疗肥胖的2型糖尿病患者的有效策略。越来越多的1型糖尿病患者也患有肥胖症及肥胖相关的合并症,但减重和代谢手术在这类患者中的作用尚不清楚。本系统评价调查了已发表的英文科学文献,以了解减重手术在肥胖的1型糖尿病患者中的效果。我们发现,这些患者通过减重手术可实现显著减重并解决合并症。尽管大多数患者的胰岛素总需求量也有所下降,但血糖控制仍然困难。文献中报道的大多数患者接受了胃旁路手术,但数据不足以推荐任何特定手术。

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