免疫缺陷疾病概述
Overview of Immunodeficiency Disorders.
作者信息
Raje Nikita, Dinakar Chitra
机构信息
Children's Mercy Hospital, University of Missouri-Kansas City, 2401 Gillham Road, Kansas City, MO 64108, USA.
Children's Mercy Hospital, University of Missouri-Kansas City, 2401 Gillham Road, Kansas City, MO 64108, USA.
出版信息
Immunol Allergy Clin North Am. 2015 Nov;35(4):599-623. doi: 10.1016/j.iac.2015.07.001. Epub 2015 Aug 25.
Abstract
The spectrum of primary immunodeficiency disorders (PIDs) is expanding. It includes typical disorders that primarily present with defective immunity as well as disorders that predominantly involve other systems and show few features of impaired immunity. The rapidly growing list of new immunodeficiency disorders and treatment modalities makes it imperative for providers to stay abreast of the latest and best management strategies. This article presents a brief overview of recent clinical advances in PIDs.
摘要
原发性免疫缺陷病（PID）的范围正在不断扩大。它包括主要表现为免疫功能缺陷的典型疾病，以及主要累及其他系统且几乎没有免疫受损特征的疾病。新的免疫缺陷病和治疗方式的清单迅速增加，这使得医疗服务提供者必须紧跟最新和最佳的管理策略。本文简要概述了PID的近期临床进展。
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本文引用的文献
1
Multicenter experience in hematopoietic stem cell transplantation for serious complications of common variable immunodeficiency.
J Allergy Clin Immunol. 2015 Apr;135(4):988-997.e6. doi: 10.1016/j.jaci.2014.11.029. Epub 2015 Jan 14.
2
Hyper-IgE syndromes: recent advances in pathogenesis, diagnostics and clinical care.
Curr Opin Hematol. 2015 Jan;22(1):12-22. doi: 10.1097/MOH.0000000000000104.
3
Regulatory T-cell deficiency and immune dysregulation, polyendocrinopathy, enteropathy, X-linked-like disorder caused by loss-of-function mutations in LRBA.
J Allergy Clin Immunol. 2015 Jan;135(1):217-27. doi: 10.1016/j.jaci.2014.10.019. Epub 2014 Nov 17.
4
GATA2 deficiency.
Curr Opin Allergy Clin Immunol. 2015 Feb;15(1):104-9. doi: 10.1097/ACI.0000000000000126.
5
Interleukin-2-inducible T-cell kinase (ITK) deficiency - clinical and molecular aspects.
J Clin Immunol. 2014 Nov;34(8):892-9. doi: 10.1007/s10875-014-0110-8. Epub 2014 Oct 24.
6
Hemophagocytic lymphohistiocytosis and primary immune deficiency disorders.
Clin Immunol. 2014 Nov;155(1):118-125. doi: 10.1016/j.clim.2014.09.008. Epub 2014 Sep 18.
7
The hereditary autoinflammatory disorders uncovered.
Autoimmun Rev. 2014 Sep;13(9):892-900. doi: 10.1016/j.autrev.2014.08.001. Epub 2014 Aug 20.
8
Newborn screening for severe combined immunodeficiency in 11 screening programs in the United States.
JAMA. 2014 Aug 20;312(7):729-38. doi: 10.1001/jama.2014.9132.
9
Transplantation outcomes for severe combined immunodeficiency, 2000-2009.
N Engl J Med. 2014 Jul 31;371(5):434-46. doi: 10.1056/NEJMoa1401177.
10
Are complement deficiencies really rare? Overview on prevalence, clinical importance and modern diagnostic approach.
Mol Immunol. 2014 Oct;61(2):110-7. doi: 10.1016/j.molimm.2014.06.030. Epub 2014 Jul 15.
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