Internal tandem duplication mutations in FLT3 gene augment chemotaxis to Cxcl12 protein by blocking the down-regulation of Rho-associated kinase via the Cxcl12/Cxcr4 signaling axis.
作者信息
Onishi Chie, Mori-Kimachi Satomi, Hirade Tomohiro, Abe Mariko, Taketani Takeshi, Suzumiya Junji, Sugimoto Toshitsugu, Yamaguchi Seiji, Kapur Reuben, Fukuda Seiji
出版信息
J Biol Chem. 2015 Nov 20;290(47):28356. doi: 10.1074/jbc.A114.568287.
Abstract
摘要
相似文献
1
Internal tandem duplication mutations in FLT3 gene augment chemotaxis to Cxcl12 protein by blocking the down-regulation of Rho-associated kinase via the Cxcl12/Cxcr4 signaling axis.
J Biol Chem. 2015 Nov 20;290(47):28356. doi: 10.1074/jbc.A114.568287.
2
Flt3 ligand and the Flt3 receptor regulate hematopoietic cell migration by modulating the SDF-1alpha(CXCL12)/CXCR4 axis.
Blood. 2005 Apr 15;105(8):3117-26. doi: 10.1182/blood-2004-04-1440. Epub 2004 Dec 23.
3
Internal tandem duplication of Flt3 modulates chemotaxis and survival of hematopoietic cells by SDF1alpha but negatively regulates marrow homing in vivo.
Exp Hematol. 2006 Aug;34(8):1041-51. doi: 10.1016/j.exphem.2006.04.001.
4
Differential regulation of CXCR4-mediated T-cell chemotaxis and mitogen-activated protein kinase activation by the membrane tyrosine phosphatase, CD45.
J Biol Chem. 2003 Mar 14;278(11):9536-43. doi: 10.1074/jbc.M211803200. Epub 2003 Jan 8.
5
Human Cytomegalovirus UL111A and US27 Gene Products Enhance the CXCL12/CXCR4 Signaling Axis via Distinct Mechanisms.
J Virol. 2018 Feb 12;92(5). doi: 10.1128/JVI.01981-17. Print 2018 Mar 1.
6
β-Arrestin1 and Signal-transducing Adaptor Molecule 1 (STAM1) Cooperate to Promote Focal Adhesion Kinase Autophosphorylation and Chemotaxis via the Chemokine Receptor CXCR4.
J Biol Chem. 2016 Dec 9;291(50):26083-26097. doi: 10.1074/jbc.M116.757138. Epub 2016 Oct 27.
7
The FLT3-ITD mutation and the expression of its downstream signaling intermediates STAT5 and Pim-1 are positively correlated with CXCR4 expression in patients with acute myeloid leukemia.
Sci Rep. 2019 Aug 21;9(1):12209. doi: 10.1038/s41598-019-48687-z.
8
Regulation of CXCR4-mediated chemotaxis and chemoinvasion of breast cancer cells.
Oncogene. 2004 Jan 8;23(1):157-67. doi: 10.1038/sj.onc.1206910.
9
CXCR4 chemokine receptor engagement modifies integrin dependent adhesion of renal carcinoma cells.
Exp Cell Res. 2007 Nov 15;313(19):4051-65. doi: 10.1016/j.yexcr.2007.07.001. Epub 2007 Jul 10.
10
CXCL14 antagonizes the CXCL12-CXCR4 signaling axis.
Biomol Concepts. 2014 May;5(2):167-73. doi: 10.1515/bmc-2014-0007.
引用本文的文献
1
Clinical Efficacies of FLT3 Inhibitors in Patients with Acute Myeloid Leukemia.
Int J Mol Sci. 2022 Oct 21;23(20):12708. doi: 10.3390/ijms232012708.
2
The research progress of targeted therapy in acute myeloid leukemia based on bibliometric analysis.
Front Oncol. 2022 Sep 2;12:957370. doi: 10.3389/fonc.2022.957370. eCollection 2022.
3
FLT3 Inhibitors in Acute Myeloid Leukemia: Current Status and Future Directions.
Mol Cancer Ther. 2017 Jun;16(6):991-1001. doi: 10.1158/1535-7163.MCT-16-0876.
Zotero 插件