Zullo Andrew R, Howe Chanelle J, Galárraga Omar
1 Brown University School of Public Health, Providence, RI, USA.
Med Care Res Rev. 2017 Apr;74(2):178-207. doi: 10.1177/1077558716629039. Epub 2016 Aug 3.
Personal prescription drug importation occurs in the United States because of the high cost of U.S. medicines and lower cost of foreign equivalents. Importation carries a risk of exposure to counterfeit (i.e., falsified, fraudulent), adulterated, and substandard drugs. Inadequate health insurance may increase the risk of importation. We use inverse probability weighted marginal structural models and data on 87,494 individuals from the 2011-2013 National Health Interview Survey to estimate the marginal association between no health insurance and importation within U.S. subpopulations. The marginal prevalence difference [95% confidence limits] for those without (prevalence = 0.031) versus those with health insurance was 0.016 [0.011, 0.021]. The prevalence difference was higher among persons who were Hispanic, born in Latin America, Russia, or Europe, traveled to developing countries, and did not use the Internet to fill prescriptions or to find health information. Health insurance coverage may effectively reduce importation, especially among particular subpopulations.
由于美国药品成本高昂而外国同类药品成本较低,美国出现了个人进口处方药的情况。进口存在接触假冒(即伪造、欺诈)、掺假和不合格药品的风险。医疗保险不足可能会增加进口风险。我们使用逆概率加权边际结构模型以及来自2011 - 2013年国家健康访谈调查的87494名个体的数据,来估计美国亚人群中无医疗保险与进口之间的边际关联。无医疗保险者(患病率 = 0.031)与有医疗保险者的边际患病率差异[95%置信区间]为0.016 [0.011, 0.021]。在西班牙裔、出生于拉丁美洲、俄罗斯或欧洲、去过发展中国家且不通过互联网填写处方或查找健康信息的人群中,患病率差异更高。医疗保险覆盖可能有效减少进口,尤其是在特定亚人群中。