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北昆士兰地区对控制不佳的 2 型糖尿病的土著卫生工作者管理的经济评估。

Economic evaluation of Indigenous health worker management of poorly controlled type 2 diabetes in north Queensland.

机构信息

Health Economics and Social Policy Group, University of South Australia, Adelaide, SA

University of South Australia, Adelaide, SA.

出版信息

Med J Aust. 2016 Mar 21;204(5):1961e-9. doi: 10.5694/mja15.00598.

Abstract

OBJECTIVE

To conduct an economic evaluation of intensive management by Indigenous health workers (IHWs) of Indigenous adults with poorly controlled type 2 diabetes in rural and remote north Queensland.

DESIGN

Cost-consequence analysis alongside a cluster randomised controlled trial of an intervention delivered between 1 March 2012 and 5 September 2013.

SETTING

Twelve primary health care services in rural and remote north Queensland communities with predominantly Indigenous populations.

PARTICIPANTS

Indigenous adults with poorly controlled type 2 diabetes (HbA1c ≥ 69 mmol/mol) and at least one comorbidity (87 people in six IHW-supported communities (IHW-S); 106 in six usual care (UC) communities).

MAIN OUTCOME MEASURES

Per person cost of the intervention; differential changes in mean HbA1c levels, percentage with extremely poor HbA1c level control, quality of life, disease progression, and number of hospitalisations.

RESULTS

The mean cost of the 18-month intervention trial was $10 060 per person ($6706 per year). The intervention was associated with a non-significantly greater reduction in mean HbA1c levels in the IHW-S group (-10.1 mmol/mol v -5.4 mmol/mol in the UC group; P = 0.17), a significant reduction in the proportion with extremely poor diabetes control (HbA1c ≥ 102 mmol/mol; P = 0.002), and a sub-significant differential reduction in hospitalisation rates for type 2 diabetes as primary diagnosis (-0.09 admissions/person/year; P = 0.06), with a net reduction in mean annual hospital costs of $646/person (P = 0.07). Quality of life utility scores declined in both groups (between-group difference, P = 0.62). Rates of disease progression were high in both groups (between-group difference, P = 0.73).

CONCLUSION

Relative to the high cost of the intervention, the IHW-S model as implemented is probably a poor investment. Incremental cost-effectiveness might be improved by a higher caseload per IHW, a longer evaluation time frame, and improved service integration. Further approaches to improving chronic disease outcomes in this very unwell population need to be explored, including holistic approaches that address the complex psychosocial, pathophysiological and environmental problems of highly disadvantaged populations.

TRIAL REGISTRATION

ANZCTR12610000812099.

摘要

目的

对原住民健康工作者(IHW)对北昆士兰农村和偏远地区 2 型糖尿病控制不佳的成年原住民进行强化管理进行经济评估。

设计

2012 年 3 月 1 日至 2013 年 9 月 5 日期间,对一项干预措施进行了成本效益分析,并进行了一项集群随机对照试验。

地点

北昆士兰农村和偏远地区原住民人口为主的 12 个初级保健服务中心。

参与者

2 型糖尿病控制不佳(HbA1c≥69mmol/mol)且至少有一种合并症的原住民成年人(6 个 IHW 支持社区中的 87 人(IHW-S);6 个常规护理(UC)社区中的 106 人)。

主要观察指标

干预措施的人均成本;平均 HbA1c 水平的差异变化、HbA1c 水平控制极差的百分比、生活质量、疾病进展和住院人数。

结果

18 个月干预试验的平均费用为每人 10060 美元(每年 6706 美元)。干预组 HbA1c 水平的降低幅度显著大于对照组(IHW-S 组为-10.1mmol/mol,UC 组为-5.4mmol/mol;P=0.17),HbA1c 水平控制极差的比例显著降低(HbA1c≥102mmol/mol;P=0.002),2 型糖尿病作为主要诊断的住院率也有显著差异(-0.09 人次/人/年;P=0.06),人均年平均住院费用降低 646 美元(P=0.07)。两组的生活质量实用评分均下降(组间差异,P=0.62)。两组的疾病进展率都很高(组间差异,P=0.73)。

结论

与干预措施的高成本相比,实施的 IHW-S 模式可能是一项糟糕的投资。通过增加每个 IHW 的病例数、延长评估时间框架和改善服务整合,可能会提高增量成本效益。需要探索进一步改善这一非常不健康人群的慢性疾病结局的方法,包括解决高度弱势群体复杂的心理社会、病理生理和环境问题的整体方法。

试验注册

ANZCTR12610000812099。

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