一种可注射的自组装胶原-金杂化水凝胶用于联合抗肿瘤光热/光动力治疗。
An Injectable Self-Assembling Collagen-Gold Hybrid Hydrogel for Combinatorial Antitumor Photothermal/Photodynamic Therapy.
机构信息
State Key Laboratory of Metastable Materials Science and Technology, Yanshan University, Qinhuangdao, 066004, P. R. China.
Hebei Key Laboratory of Applied Chemistry, School of Environmental and Chemical Engineering, Yanshan University, Qinhuangdao, 066004, P. R. China.
出版信息
Adv Mater. 2016 May;28(19):3669-76. doi: 10.1002/adma.201600284. Epub 2016 Mar 17.
An injectable and self-healing collagen-gold hybrid hydrogel is spontaneously formed by electrostatic self-assembly and subsequent biomineralization. It is demonstrated that such collagen-based hydrogels may be used as an injectable material for local delivery of therapeutic agents, showing enhanced antitumor efficacy.
一种可注射和自修复的胶原-金杂化水凝胶通过静电自组装和随后的生物矿化自发形成。研究表明，这种基于胶原的水凝胶可用作治疗剂的局部递送的可注射材料，显示出增强的抗肿瘤功效。
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