众多复杂性状的多效性。
A plethora of pleiotropy across complex traits.
机构信息
Queensland Brain Institute, The University of Queensland, Brisbane, Queensland, Australia.
出版信息
Nat Genet. 2016 Jun 28;48(7):707-8. doi: 10.1038/ng.3604.
DOI:10.1038/ng.3604
PMID:27350602
Abstract
A new analysis has identified hundreds of loci that are associated with multiple traits or diseases by comparing genome-wide association study (GWAS) data for 42 complex traits. The study uses the power of GWAS to provide evidence of pairs of traits with a likely causal relationship.
摘要
一项新的分析通过比较 42 种复杂性状的全基因组关联研究 (GWAS) 数据，确定了数百个与多种性状或疾病相关的基因座。该研究利用 GWAS 的力量，提供了具有可能因果关系的性状对的证据。
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