School of Pharmacy, Memorial University of Newfoundland, St. John's, Canada.
Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.
Ophthalmology. 2016 Dec;123(12):2571-2580. doi: 10.1016/j.ophtha.2016.08.021. Epub 2016 Oct 7.
To determine the incremental cost-effectiveness of a new telemedicine technician-based assessment relative to an existing model of family physician (FP)-based assessment of diabetic retinopathy (DR) in Singapore from the health system and societal perspectives.
Model-based, cost-effectiveness analysis of the Singapore Integrated Diabetic Retinopathy Program (SiDRP).
A hypothetical cohort of patients aged 55 years with type 2 diabetes previously not screened for DR.
The SiDRP is a new telemedicine-based DR screening program using trained technicians to assess retinal photographs. We compared the cost-effectiveness of SiDRP with the existing model in which FPs assess photographs. We developed a hybrid decision tree/Markov model to simulate the costs, effectiveness, and incremental cost-effectiveness ratio (ICER) of SiDRP relative to FP-based DR screening over a lifetime horizon. We estimated the costs from the health system and societal perspectives. Effectiveness was measured in terms of quality-adjusted life-years (QALYs). Result robustness was calculated using deterministic and probabilistic sensitivity analyses.
The ICER.
From the societal perspective that takes into account all costs and effects, the telemedicine-based DR screening model had significantly lower costs (total cost savings of S$173 per person) while generating similar QALYs compared with the physician-based model (i.e., 13.1 QALYs). From the health system perspective that includes only direct medical costs, the cost savings are S$144 per person. By extrapolating these data to approximately 170 000 patients with diabetes currently being screened yearly for DR in Singapore's primary care polyclinics, the present value of future cost savings associated with the telemedicine-based model is estimated to be S$29.4 million over a lifetime horizon.
While generating similar health outcomes, the telemedicine-based DR screening using technicians in the primary care setting saves costs for Singapore compared with the FP model. Our data provide a strong economic rationale to expand the telemedicine-based DR screening program in Singapore and elsewhere.
从卫生系统和社会角度出发,确定基于新远程医疗技术员评估的成本效益是否优于新加坡现有的基于家庭医生(FP)评估糖尿病视网膜病变(DR)的模型。
新加坡综合糖尿病视网膜病变计划(SiDRP)的基于模型的成本效益分析。
一组假设的年龄在 55 岁、患有 2 型糖尿病且以前未接受过 DR 筛查的患者。
SiDRP 是一种新的基于远程医疗的 DR 筛查计划,使用经过培训的技术员评估视网膜照片。我们将 SiDRP 的成本效益与现有的模型进行了比较,后者由 FP 评估照片。我们开发了一种混合决策树/马尔可夫模型,以模拟 SiDRP 相对于基于 FP 的 DR 筛查在终生范围内的成本、效果和增量成本效益比(ICER)。我们从卫生系统和社会角度估算了成本。效果以质量调整生命年(QALY)来衡量。使用确定性和概率敏感性分析计算结果的稳健性。
ICER。
从考虑所有成本和效果的社会角度来看,与基于医生的模型相比,基于远程医疗的 DR 筛查模型具有显著更低的成本(每人节省 173 新元),同时产生的 QALYs 相似(即 13.1 QALYs)。从仅包括直接医疗费用的卫生系统角度来看,成本节省为每人 144 新元。将这些数据外推到新加坡初级保健诊所中目前每年接受 DR 筛查的大约 170000 名糖尿病患者,基于远程医疗的模型在终生范围内预计可节省 2940 万新元的未来成本节约。
在产生相似健康结果的基础上,基于远程医疗的技术员在初级保健环境中的 DR 筛查在新加坡相对于 FP 模型节省了成本。我们的数据为在新加坡和其他地方扩大基于远程医疗的 DR 筛查计划提供了强有力的经济依据。