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肥胖对并发症及手术结果的影响:融合与非融合腰椎手术的比较

Impact of obesity on complications and outcomes: a comparison of fusion and nonfusion lumbar spine surgery.

作者信息

Onyekwelu Ikemefuna, Glassman Steven D, Asher Anthony L, Shaffrey Christopher I, Mummaneni Praveen V, Carreon Leah Y

机构信息

Department of Orthopaedic Surgery, University of Louisville School of Medicine.

Norton Leatherman Spine Center, Louisville, Kentucky.

出版信息

J Neurosurg Spine. 2017 Feb;26(2):158-162. doi: 10.3171/2016.7.SPINE16448. Epub 2016 Oct 14.

Abstract

OBJECTIVE Prior studies have shown obesity to be associated with higher complication rates but equivalent clinical outcomes following lumbar spine surgery. These findings have been reproducible across lumbar spine surgery in general and for lumbar fusion specifically. Nevertheless, surgeons seem inclined to limit the extent of surgery, perhaps opting for decompression alone rather than decompression plus fusion, in obese patients. The purpose of this study was to ascertain any difference in clinical improvement or complication rates between obese and nonobese patients following decompression alone compared with decompression plus fusion for lumbar spinal stenosis (LSS). METHODS The Quality Outcomes Database (QOD), formerly known as the National Neurosurgery Quality and Outcomes Database (NQOD), was queried for patients who had undergone decompression plus fusion (D+F group) versus decompression alone (D+0 group) for LSS and were stratified by a body mass index (BMI) ≥ 30 kg/m (obese) or < 30 kg/m (nonobese). Demographic, surgical, and health-related quality of life data were compared. RESULTS In the nonobese cohort, 947 patients underwent decompression alone and 319 underwent decompression plus fusion. In the obese cohort, 844 patients had decompression alone and 337 had decompression plus fusion. There were no significant differences in the Oswestry Disability Index score or in leg pain improvement at 12 months when comparing decompression with fusion to decompression without fusion in either obese or nonobese cohorts. However, absolute improvement in back pain was less in the obese group when decompression alone had been performed. Blood loss and operative time were lowest in the nonobese D+0 cohort and were higher in obese patients with or without fusion. Obese patients had a longer hospital stay (4.1 days) than the nonobese patients (3.3 days) when fusion had been performed. In-hospital stay was similar in both obese and nonobese D+0 cohorts. No significant differences were seen in 30-day readmission rates among the 4 cohorts. CONCLUSIONS Consistent with the prior literature, equivalent clinical outcomes were found among obese and non-obese patients treated for LSS. In addition, no difference in clinical outcomes as related to the extent of the surgical procedure was observed between obese and nonobese patients. Within the D+0 group, the nonobese patients had slightly better back pain scores at 2 years postoperatively. There may be a higher blood product requirement in obese patients following spine surgery, as well as an extended hospital stay, when fusion is performed. While obesity may influence the decision for or against surgery, the data suggest that obesity should not necessarily alter the appropriate procedure for well-selected surgical candidates.

摘要

目的 先前的研究表明,肥胖与腰椎手术后较高的并发症发生率相关,但临床结局相当。这些发现已在一般的腰椎手术中以及具体的腰椎融合手术中得到重现。然而,外科医生似乎倾向于限制手术范围,在肥胖患者中可能选择单纯减压而非减压加融合。本研究的目的是确定在单纯减压与减压加融合治疗腰椎管狭窄症(LSS)后,肥胖患者与非肥胖患者在临床改善或并发症发生率方面是否存在差异。方法 在质量结果数据库(QOD,前身为国家神经外科质量与结果数据库,NQOD)中查询接受LSS减压加融合(D+F组)与单纯减压(D+0组)的患者,并根据体重指数(BMI)≥30 kg/m²(肥胖)或<30 kg/m²(非肥胖)进行分层。比较人口统计学、手术和健康相关生活质量数据。结果 在非肥胖队列中,947例患者接受了单纯减压,319例接受了减压加融合。在肥胖队列中,844例患者接受了单纯减压,337例接受了减压加融合。在肥胖或非肥胖队列中,将减压加融合与单纯减压进行比较时,12个月时的Oswestry功能障碍指数评分或腿痛改善情况没有显著差异。然而,在进行单纯减压时,肥胖组的背痛绝对改善较小。非肥胖D+0队列中的失血量和手术时间最低,肥胖患者无论是否进行融合,失血量和手术时间都更高。在进行融合时,肥胖患者的住院时间(4.1天)比非肥胖患者(3.3天)更长。肥胖和非肥胖D+0队列的住院时间相似。4个队列的30天再入院率没有显著差异。结论 与先前的文献一致,在接受LSS治疗的肥胖患者和非肥胖患者中发现了相当的临床结局。此外,在肥胖患者和非肥胖患者之间,未观察到与手术范围相关的临床结局差异。在D+0组中,非肥胖患者术后2年的背痛评分略好。脊柱手术后肥胖患者可能需要更多的血液制品,并且在进行融合时住院时间会延长。虽然肥胖可能会影响手术决策,但数据表明,肥胖不一定会改变为精心挑选的手术候选人选择的合适手术方式。

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