Immunosuppressive T cells foster pancreatic carcinogenesis.
作者信息
Mondragón Laura, Kroemer Guido, Galluzzi Lorenzo
机构信息
Equipe 11 labellisée Ligue contre le Cancer, Center de Recherche des Cordeliers, Paris, France; INSERM, U1138, Paris, France; Université Paris Descartes/Paris V, Sorbonne Paris Cité, Paris, France; Université Pierre et Marie Curie/Paris VI, Paris, France; Gustave Roussy Comprehensive Cancer Institute, Villejuif, France.
Equipe 11 labellisée Ligue contre le Cancer, Center de Recherche des Cordeliers, Paris, France; INSERM, U1138, Paris, France; Université Paris Descartes/Paris V, Sorbonne Paris Cité, Paris, France; Université Pierre et Marie Curie/Paris VI, Paris, France; Metabolomics and Cell Biology Platforms, Gustave Roussy Comprehensive Cancer Institute, Villejuif, France; Pôle de Biologie, Hopitâl Européen George Pompidou, AP-HP, Paris, France; Department of Women's and Children's Health, Karolinska University Hospital, Stockholm, Sweden.
出版信息
Oncoimmunology. 2016 Sep 27;5(11):e1237328. doi: 10.1080/2162402X.2016.1237328. eCollection 2016.
Abstract
摘要
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Nat Rev Immunol. 2017 Feb;17(2):97-111. doi: 10.1038/nri.2016.107. Epub 2016 Oct 17.
2
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3
Immunological Effects of Conventional Chemotherapy and Targeted Anticancer Agents.
Cancer Cell. 2015 Dec 14;28(6):690-714. doi: 10.1016/j.ccell.2015.10.012.
4
γδ T cells in cancer.
Nat Rev Immunol. 2015 Nov;15(11):683-91. doi: 10.1038/nri3904. Epub 2015 Oct 9.
5
The prognostic landscape of genes and infiltrating immune cells across human cancers.
Nat Med. 2015 Aug;21(8):938-945. doi: 10.1038/nm.3909. Epub 2015 Jul 20.
6
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Oncoimmunology. 2015 Apr 28;4(6):e1006088. doi: 10.1080/2162402X.2015.1006088. eCollection 2015 Jun.
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