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“周末战士”和其他休闲时间体力活动模式与全因、心血管疾病和癌症死亡率风险的关联。

Association of "Weekend Warrior" and Other Leisure Time Physical Activity Patterns With Risks for All-Cause, Cardiovascular Disease, and Cancer Mortality.

机构信息

Diabetes Research Centre, College of Medicine, Biological Sciences and Psychology, University of Leicester, Leicester General Hospital, Leicester, England2currently with the School of Sport, Exercise, and Health Sciences, National Centre for Sport and Exercise Medicine-East Midlands, Loughborough University, Loughborough, England.

Department of Epidemiology, School of Public Health, Harvard University, Harvard Medical School, Brigham and Women's Hospital, Boston, Massachusetts.

出版信息

JAMA Intern Med. 2017 Mar 1;177(3):335-342. doi: 10.1001/jamainternmed.2016.8014.

Abstract

IMPORTANCE

More research is required to clarify the association between physical activity and health in "weekend warriors" who perform all their exercise in 1 or 2 sessions per week.

OBJECTIVE

To investigate associations between the weekend warrior and other physical activity patterns and the risks for all-cause, cardiovascular disease (CVD), and cancer mortality.

DESIGN, SETTING, AND PARTICIPANTS: This pooled analysis of household-based surveillance studies included 11 cohorts of respondents to the Health Survey for England and Scottish Health Survey with prospective linkage to mortality records. Respondents 40 years or older were included in the analysis. Data were collected from 1994 to 2012 and analyzed in 2016.

EXPOSURES

Self-reported leisure time physical activity, with activity patterns defined as inactive (reporting no moderate- or vigorous-intensity activities), insufficiently active (reporting <150 min/wk in moderate-intensity and <75 min/wk in vigorous-intensity activities), weekend warrior (reporting ≥150 min/wk in moderate-intensity or ≥75 min/wk in vigorous-intensity activities from 1 or 2 sessions), and regularly active (reporting ≥150 min/wk in moderate-intensity or ≥75 min/wk in vigorous-intensity activities from ≥3 sessions). The insufficiently active participants were also characterized by physical activity frequency.

MAIN OUTCOMES AND MEASURES

All-cause, CVD, and cancer mortality ascertained from death certificates.

RESULTS

Among the 63 591 adult respondents (45.9% male; 44.1% female; mean [SD] age, 58.6 [11.9] years), 8802 deaths from all causes, 2780 deaths from CVD, and 2526 from cancer occurred during 561 159 person-years of follow-up. Compared with the inactive participants, the hazard ratio (HR) for all-cause mortality was 0.66 (95% CI, 0.62-0.72) in insufficiently active participants who reported 1 to 2 sessions per week, 0.70 (95% CI, 0.60-0.82) in weekend warrior participants, and 0.65 (95% CI, 0.58-0.73) in regularly active participants. Compared with the inactive participants, the HR for CVD mortality was 0.60 (95% CI, 0.52-0.69) in insufficiently active participants who reported 1 or 2 sessions per week, 0.60 (95% CI, 0.45-0.82) in weekend warrior participants, and 0.59 (95% CI, 0.48-0.73) in regularly active participants. Compared with the inactive participants, the HR for cancer mortality was 0.83 (95% CI, 0.73-0.94) in insufficiently active participants who reported 1 or 2 sessions per week, 0.82 (95% CI, 0.63-1.06) in weekend warrior participants, and 0.79 (95% CI, 0.66-0.94) in regularly active participants.

CONCLUSIONS AND RELEVANCE

Weekend warrior and other leisure time physical activity patterns characterized by 1 or 2 sessions per week may be sufficient to reduce all-cause, CVD, and cancer mortality risks regardless of adherence to prevailing physical activity guidelines.

摘要

重要提示

还需要更多的研究来阐明“周末战士”(每周仅进行 1 或 2 次运动的人)的体力活动与健康之间的关系。

目的

研究“周末战士”和其他体力活动模式与全因、心血管疾病(CVD)和癌症死亡率风险之间的关系。

设计、地点和参与者:本研究采用英格兰卫生调查和苏格兰卫生调查的基于家庭的监测研究的汇总分析,前瞻性地将死亡率记录与参与者联系起来。分析包括年龄在 40 岁及以上的 11 个队列的受访者。数据收集于 1994 年至 2012 年,于 2016 年进行分析。

暴露情况

自我报告的休闲时间体力活动,活动模式定义为不活跃(报告没有中等强度或剧烈强度的活动)、不充分活跃(报告每周中等强度活动<150 分钟且每周剧烈强度活动<75 分钟)、周末战士(报告每周中等强度活动≥150 分钟或每周剧烈强度活动≥75 分钟,且仅来自 1 或 2 次运动)和定期活跃(报告每周中等强度活动≥150 分钟或每周剧烈强度活动≥75 分钟,且来自≥3 次运动)。不活跃的参与者还根据体力活动频率进行了特征描述。

主要结果和测量

通过死亡证明确定全因、CVD 和癌症死亡率。

结果

在 63591 名成年受访者(45.9%为男性;44.1%为女性;平均[标准差]年龄 58.6[11.9]岁)中,561159 人年的随访期间发生了 8802 例全因死亡、2780 例 CVD 死亡和 2526 例癌症死亡。与不活跃的参与者相比,每周报告 1 到 2 次运动的不活跃参与者的全因死亡率 HR 为 0.66(95%CI,0.62-0.72),每周报告 1 次或 2 次运动的周末战士参与者为 0.70(95%CI,0.60-0.82),每周报告≥3 次运动的定期活跃参与者为 0.65(95%CI,0.58-0.73)。与不活跃的参与者相比,每周报告 1 到 2 次运动的不活跃参与者的 CVD 死亡率 HR 为 0.60(95%CI,0.52-0.69),每周报告 1 次或 2 次运动的周末战士参与者为 0.60(95%CI,0.45-0.82),每周报告≥3 次运动的定期活跃参与者为 0.59(95%CI,0.48-0.73)。与不活跃的参与者相比,每周报告 1 到 2 次运动的不活跃参与者的癌症死亡率 HR 为 0.83(95%CI,0.73-0.94),每周报告 1 次或 2 次运动的周末战士参与者为 0.82(95%CI,0.63-1.06),每周报告≥3 次运动的定期活跃参与者为 0.79(95%CI,0.66-0.94)。

结论和相关性

周末战士和其他每周仅进行 1 或 2 次运动的休闲时间体力活动模式可能足以降低全因、CVD 和癌症死亡率风险,无论是否符合现行体力活动指南。

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