一种基于吩嗪-巴比妥酸的比色和比率近红外荧光探针，用于灵敏区分生物硫醇及其在TiO传感器装置中的应用。
A phenazine-barbituric acid based colorimetric and ratiometric near-infrared fluorescent probe for sensitively differentiating biothiols and its application in TiO sensor devices.
作者信息
Zhang Xiao, Yan Yongchao, Hang Yandi, Wang Jian, Hua Jianli, Tian He
机构信息
Key Laboratory for Advanced Materials, Institute of Fine Chemicals, College of Chemistry and Molecular Engineering, East China University of Science and Technology, 130 Meilong Road, Shanghai, 200237, P. R. China.
出版信息
Chem Commun (Camb). 2017 May 23;53(42):5760-5763. doi: 10.1039/c7cc01925d.
A new colorimetric and ratiometric near-infrared fluorescent probe based on phenazine-barbituric acid was developed to ultrasensitively detect biothiols. The favorable ratiometric changes helped the imaging and differentiation of Cys in living cells. Besides, the probe was successfully employed to construct TiO sensor devices, which could quantify Hcy concentration in serum.
基于吩嗪-巴比妥酸开发了一种新型比色和比率近红外荧光探针，用于超灵敏检测生物硫醇。良好的比率变化有助于活细胞中半胱氨酸（Cys）的成像和区分。此外，该探针成功用于构建TiO传感器装置，可定量血清中的同型半胱氨酸（Hcy）浓度。
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