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1980年至2014年美国各县预期寿命的不平等:时间趋势和主要驱动因素

Inequalities in Life Expectancy Among US Counties, 1980 to 2014: Temporal Trends and Key Drivers.

作者信息

Dwyer-Lindgren Laura, Bertozzi-Villa Amelia, Stubbs Rebecca W, Morozoff Chloe, Mackenbach Johan P, van Lenthe Frank J, Mokdad Ali H, Murray Christopher J L

机构信息

Institute for Health Metrics and Evaluation, University of Washington, Seattle.

Department of Public Health, Erasmus MC, Rotterdam, Netherlands.

出版信息

JAMA Intern Med. 2017 Jul 1;177(7):1003-1011. doi: 10.1001/jamainternmed.2017.0918.

Abstract

IMPORTANCE

Examining life expectancy by county allows for tracking geographic disparities over time and assessing factors related to these disparities. This information is potentially useful for policy makers, clinicians, and researchers seeking to reduce disparities and increase longevity.

OBJECTIVE

To estimate annual life tables by county from 1980 to 2014; describe trends in geographic inequalities in life expectancy and age-specific risk of death; and assess the proportion of variation in life expectancy explained by variation in socioeconomic and race/ethnicity factors, behavioral and metabolic risk factors, and health care factors.

DESIGN, SETTING, AND PARTICIPANTS: Annual county-level life tables were constructed using small area estimation methods from deidentified death records from the National Center for Health Statistics (NCHS), and population counts from the US Census Bureau, NCHS, and the Human Mortality Database. Measures of geographic inequality in life expectancy and age-specific mortality risk were calculated. Principal component analysis and ordinary least squares regression were used to examine the county-level association between life expectancy and socioeconomic and race/ethnicity factors, behavioral and metabolic risk factors, and health care factors.

EXPOSURES

County of residence.

MAIN OUTCOMES AND MEASURES

Life expectancy at birth and age-specific mortality risk.

RESULTS

Counties were combined as needed to create stable units of analysis over the period 1980 to 2014, reducing the number of areas analyzed from 3142 to 3110. In 2014, life expectancy at birth for both sexes combined was 79.1 (95% uncertainty interval [UI], 79.0-79.1) years overall, but differed by 20.1 (95% UI, 19.1-21.3) years between the counties with the lowest and highest life expectancy. Absolute geographic inequality in life expectancy increased between 1980 and 2014. Over the same period, absolute geographic inequality in the risk of death decreased among children and adolescents, but increased among older adults. Socioeconomic and race/ethnicity factors, behavioral and metabolic risk factors, and health care factors explained 60%, 74%, and 27% of county-level variation in life expectancy, respectively. Combined, these factors explained 74% of this variation. Most of the association between socioeconomic and race/ethnicity factors and life expectancy was mediated through behavioral and metabolic risk factors.

CONCLUSIONS AND RELEVANCE

Geographic disparities in life expectancy among US counties are large and increasing. Much of the variation in life expectancy among counties can be explained by a combination of socioeconomic and race/ethnicity factors, behavioral and metabolic risk factors, and health care factors. Policy action targeting socioeconomic factors and behavioral and metabolic risk factors may help reverse the trend of increasing disparities in life expectancy in the United States.

摘要

重要性

按县审查预期寿命有助于追踪地理差异随时间的变化,并评估与这些差异相关的因素。这些信息对于寻求减少差异和延长寿命的政策制定者、临床医生和研究人员可能有用。

目的

估计1980年至2014年各县的年度生命表;描述预期寿命和特定年龄死亡风险的地理不平等趋势;评估社会经济和种族/族裔因素、行为和代谢风险因素以及医疗保健因素的差异对预期寿命差异的解释比例。

设计、设置和参与者:使用小区域估计方法,根据国家卫生统计中心(NCHS)的匿名死亡记录以及美国人口普查局、NCHS和人类死亡率数据库的人口计数,构建年度县级生命表。计算预期寿命和特定年龄死亡风险的地理不平等指标。使用主成分分析和普通最小二乘法回归来研究预期寿命与社会经济和种族/族裔因素、行为和代谢风险因素以及医疗保健因素之间的县级关联。

暴露因素

居住县。

主要结局和指标

出生时预期寿命和特定年龄死亡风险。

结果

根据需要合并各县,以在1980年至2014年期间创建稳定的分析单位,将分析的地区数量从3142个减少到3110个。2014年,男女合并的出生时预期寿命总体为79.1岁(95%不确定区间[UI],79.0 - 79.1),但预期寿命最低和最高的县之间相差20.1岁(95% UI,19.1 - 21.3)。1980年至2014年期间,预期寿命的绝对地理不平等有所增加。在同一时期,儿童和青少年的死亡风险绝对地理不平等有所下降,但老年人的有所增加。社会经济和种族/族裔因素、行为和代谢风险因素以及医疗保健因素分别解释了县级预期寿命差异的60%、74%和27%。综合起来,这些因素解释了这种差异的74%。社会经济和种族/族裔因素与预期寿命之间的大多数关联是通过行为和代谢风险因素介导的。

结论及相关性

美国各县之间预期寿命的地理差异很大且在增加。各县预期寿命的许多差异可以由社会经济和种族/族裔因素、行为和代谢风险因素以及医疗保健因素的综合作用来解释。针对社会经济因素以及行为和代谢风险因素的政策行动可能有助于扭转美国预期寿命差异不断扩大的趋势。

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