基于网络的非编码 RNA 资源在癌症研究中的全面综述。
A comprehensive review of web-based non-coding RNA resources for cancer research.
机构信息
Yunnan Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, Yunnan, 650500, China.
Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming, Yunnan, 650500, China.
出版信息
Cancer Lett. 2017 Oct 28;407:1-8. doi: 10.1016/j.canlet.2017.08.015. Epub 2017 Aug 18.
Non-coding RNAs include many kinds of RNAs that did not encode proteins. Recent evidences reveal that ncRNAs play critical roles in initiation and progression of cancers. But it is not easy for cancer biologists and medical doctors to easily know the potential roles of ncRNAs in cancer and retrieve the information of ncRNAs under their investigations. To make the available web-based resources more accessible and understandable, we made a comprehensive review for 49 web-based resources of three types of ncRNAs, i.e., microRNAs (miRNAs), long non-coding RNAs (lncRNAs) and circular RNAs (circRNAs). We also listed some preferred resources for 6 different types of analyses related to ncRNAs.
非编码 RNA 包括许多不编码蛋白质的 RNA。最近的证据表明，ncRNAs 在癌症的发生和发展中起着关键作用。但是，癌症生物学家和医生很难轻易了解 ncRNAs 在癌症中的潜在作用，也很难检索他们研究中 ncRNAs 的信息。为了使现有的基于网络的资源更易于访问和理解，我们对三种类型的 ncRNAs（microRNAs (miRNAs)、长非编码 RNA (lncRNAs) 和环状 RNA (circRNAs) 的 49 个基于网络的资源进行了全面的综述。我们还列出了与 ncRNAs 相关的 6 种不同类型分析的一些首选资源。
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