Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Addis Continental Institute of Public Health, Addis Ababa, Ethiopia.
Matern Child Nutr. 2018 Apr;14(2):e12519. doi: 10.1111/mcn.12519. Epub 2017 Oct 10.
A scaled up and integrated outpatient therapeutic feeding programme (OTP) brings the treatment of severely malnourished children closer to the community. This study assessed recovery from severe acute malnutrition (SAM), fatality, and acute malnutrition up to 14 weeks after admission to a programme integrated in the primary health care system. In this cohort study, 1,048 children admitted to 94 OTPs in Southern Ethiopia were followed for 14 weeks. Independent anthropometric measurements and information on treatment outcome were collected at four home visits. Only 32.7% (248/759) of children with SAM on admission fulfilled the programme recovery criteria at the time of discharge (i.e., gained 15% in weight, or oedema, if present at admission, was resolved at discharge). Of all children admitted to the programme for whom nutritional assessment was done 14 weeks later, 34.6% (321/928) were severely malnourished, and 37.5% (348/928) were moderately malnourished; thus, 72.1% were acutely malnourished. Of the children, 27/982 (2.7%) had died by 14 weeks, of whom all but one had SAM on admission. Children with severe oedema on admission had the highest fatality rate (12.0%, 9/75). The median length of admission to the programme was 6.6 weeks (interquartile range: 5.3, 8.4 weeks). Despite children participating for the recommended duration of the programme, many children with SAM were discharged still acutely malnourished and without reaching programme criteria for recovery. For better outcome of OTP, constraints in service provision by the health system as well as challenges of service utilization by the beneficiaries should be identified and addressed.
扩大和整合门诊治疗喂养方案(OTP)将严重营养不良儿童的治疗工作更贴近社区。本研究评估了在初级卫生保健系统中整合的方案中接受治疗的严重急性营养不良(SAM)儿童的康复情况、死亡率以及在入院后 14 周时的急性营养不良情况。在这项队列研究中,对埃塞俄比亚南部 94 个 OTP 收治的 1048 名儿童进行了 14 周的随访。在四次家访中,独立进行了人体测量并收集了有关治疗结果的信息。入院时患有 SAM 的儿童中只有 32.7%(248/759)符合出院时的方案康复标准(即体重增加 15%,或入院时存在水肿,则在出院时已消退)。在所有接受方案营养评估的入院儿童中,14 周后有 34.6%(321/928)仍患有严重营养不良,37.5%(348/928)患有中度营养不良;因此,72.1%的儿童患有急性营养不良。在这些儿童中,有 27/982(2.7%)在 14 周内死亡,其中除 1 人外均在入院时患有 SAM。入院时严重水肿的儿童死亡率最高(12.0%,9/75)。入院方案的中位时间为 6.6 周(四分位间距:5.3,8.4 周)。尽管儿童按照方案建议的时间接受治疗,但许多患有 SAM 的儿童出院时仍患有急性营养不良,且未达到方案的康复标准。为了改善 OTP 的结果,应确定并解决卫生系统在服务提供方面的限制以及受益人在利用服务方面的挑战。