罗丹明-肉桂醛衍生物对锌离子的“开启型”荧光和比色检测

"Turn-On" Fluorescent and Colorimetric Detection of Zn Ions by Rhodamine-Cinnamaldehyde Derivative.

作者信息

Lee Sang-Oh, An Kyoung-Lyong, Shin Seung-Rim, Jun Kun, Naveen Mergu, Son Young-A

机构信息

Department of Advanced Organic Materials Engineering, Chungnam National University, 220 Gung-dong, Yuseong-gu, Daejeon, 34134, South Korea.

Center for Interface Materials and Chemical Engineering, Korea Research Institute of Chemical Technology, Daejeon, 34114, South Korea.

出版信息

J Nanosci Nanotechnol. 2018 Aug 1;18(8):5333-5340. doi: 10.1166/jnn.2018.15380.

DOI:10.1166/jnn.2018.15380

PMID:29458585

Abstract

We report the design and synthesis of a novel chemosensor (Rh6G-Cin) rhodamine-based indicator for selective detection of Zn2+ ion. Rh6G-Cin displayed high selectivity towards Zn2+ from various metal ions, including Ca2+, Ag+, Cd2+, Co2+, Cu2+, Al3+, Zn2+, Cr3+, Ba2+, Fe2+, Fe3+, Gd3+, Hg2+, Mg2+, Mn2+, Nd3+, Pb2+, Sr2+ and Ni2+, and the resultant complex is [Rh6G-Cin-Zn2+]. The obvious change from colorless to pink upon the addition of Zn2+ could make it a suitable "naked eye" indicator for Zn2+. More significantly, the sensor displayed a remarkable colorless to yellowish green fluorescence switch in the presence of Zn2+ ions. The ring-opening mechanism of the rhodamine spirolactam was induced by Zn2+ binding, and the 3:1 stoichiometric structure between Rh6G-Cin and Zn2+ was adequately supported by the Job's plot evaluation, optical titration and 1H NMR results.

摘要

我们报道了一种新型化学传感器（Rh6G-Cin）的设计与合成，它是一种基于罗丹明的指示剂，用于选择性检测Zn2+离子。Rh6G-Cin对包括Ca2+、Ag+、Cd2+、Co2+、Cu2+、Al3+、Zn2+、Cr3+、Ba2+、Fe2+、Fe3+、Gd3+、Hg2+、Mg2+、Mn2+、Nd3+、Pb2+、Sr2+和Ni2+在内的各种金属离子中的Zn2+表现出高选择性，形成的络合物为[Rh6G-Cin-Zn2+]。加入Zn2+后从无色变为粉红色的明显变化使其成为一种适用于Zn2+的“肉眼”指示剂。更重要的是，该传感器在存在Zn2+离子时显示出显著的从无色到黄绿色的荧光开关。罗丹明螺内酰胺的开环机制是由Zn2+结合诱导的，Job曲线评估、光学滴定和1H NMR结果充分支持了Rh6G-Cin与Zn2+之间3:1的化学计量结构。