Munchey Ratree, Pongmesa Tipaporn
Department of Pharmacy, Nampad Hospital, Uttaradit, Thailand.
Department of Pharmacy, Faculty of Pharmacy, Silpakorn University, Nakhon Pathom, Thailand.
Value Health Reg Issues. 2018 May;15:76-81. doi: 10.1016/j.vhri.2017.08.012. Epub 2017 Oct 16.
To assess the health-related quality of life and functional ability of patients with rheumatoid arthritis (RA) using the Thai EuroQol five-dimensional questionnaire (EQ-5D) and the Thai Health Assessment Questionnaire (HAQ), and to analyze correlations between the scores from both questionnaires.
This cross-sectional study was conducted among 221 patients with RA aged 18 years or older at a tertiary care hospital in Thailand. Data collection methods included individual patient interviews and data gathering from medical records. The correlations between the EQ-5D and HAQ scores were analyzed using Spearman's rank correlation coefficients.
Most patients were female (78.3%), aged 41 to 60 years (57.0%), having had RA for 12 to 60 months (43.0%), and being in an active disease state (60.6%). From the EQ-5D, most patients reported no problems in each dimension, except for mobility and pain/discomfort. For the HAQ, most patients reported no difficulty for almost all activities, except for arising. The medians (interquartile ranges) for the EQ-5D utility, EuroQol visual analogue scale (EQ VAS), and HAQ scores were 0.65 (0.55-0.73), 70 (50-80), and 0.25 (0.00-0.81), respectively. The Spearman's rank correlation coefficients were 0.42 for the EQ-5D utility and EQ VAS scores (P = 0.01), -0.65 for the EQ-5D utility and HAQ scores (P < 0.001), and -0.39 for the EQ VAS and HAQ scores (P < 0.001).
The health-related quality of life and functional ability of most patients in our study were partially affected by the disease. The EQ-5D and HAQ scores significantly correlated at a moderate to strong level.
使用泰国版欧洲五维健康量表(EQ - 5D)和泰国健康评估问卷(HAQ)评估类风湿关节炎(RA)患者的健康相关生活质量和功能能力,并分析两份问卷得分之间的相关性。
这项横断面研究在泰国一家三级护理医院对221名18岁及以上的RA患者进行。数据收集方法包括对患者进行个体访谈以及从病历中收集数据。使用Spearman等级相关系数分析EQ - 5D和HAQ得分之间的相关性。
大多数患者为女性(78.3%),年龄在41至60岁之间(57.0%),患RA 12至60个月(43.0%),且处于疾病活动状态(60.6%)。根据EQ - 5D,除了活动能力和疼痛/不适维度外,大多数患者在其他维度均报告无问题。对于HAQ,除了起床活动外,大多数患者在几乎所有活动方面均报告无困难。EQ - 5D效用值、欧洲五维健康量表视觉模拟量表(EQ VAS)和HAQ得分的中位数(四分位间距)分别为0.65(0.55 - 0.73)、70(50 - 80)和0.25(0.00 - 0.81)。EQ - 5D效用值与EQ VAS得分的Spearman等级相关系数为0.42(P = 0.01),EQ - 5D效用值与HAQ得分的相关系数为 - 0.65(P < 0.001),EQ VAS与HAQ得分的相关系数为 - 0.39(P < 0.001)。
我们研究中大多数患者的健康相关生活质量和功能能力受到疾病的部分影响。EQ - 5D和HAQ得分在中等到强的水平上显著相关。