Department of Public Health, School of Health Sciences and Practice, New York Medical College, Valhalla, New York.
Department of Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania.
J Am Geriatr Soc. 2018 Jul;66(7):1303-1310. doi: 10.1111/jgs.15390. Epub 2018 Apr 23.
To characterize the distribution of an index of healthy aging-the Chinese Healthy Aging Index (CHAI)-in Chinese adults aged 60 and older according to sociodemographic characteristics and geographic region and to examine the association between the CHAI and mortality, disability, and functional limitation over 4 years.
Nationally representative cohort study.
China Health and Retirement Longitudinal Study.
Chinese adults aged 60 and older (N=3,740).
Six CHAI components (systolic blood pressure, peak expiratory flow, Telephone Interview for Cognitive Status, estimated glomerular filtration rate, fasting glucose, C-reactive protein) were scored 0 (healthiest), 1, and 2 (unhealthiest) according to sex-specific tertiles or clinically relevant cut-points and summed to construct the CHAI (range 0-12).
Mean CHAI score was 5.6; 5.7% had a score of 0 to 2 (healthiest), 23.0% a score of 3 or 4, 37.5% a score of 5 or 6, and 33.8% a score of 7 to 12 (unhealthiest). Participants who were younger, more educated, and married were much more likely to have an ideal CHAI profile (score 0-2). Age-adjusted prevalence of an ideal CHAI profile ranged from 1.7% in the south to 8.1% in the north. After multivariable adjustment, persons with a CHAI score of 3 to 12 had substantially higher odds of mortality, disability, and functional limitation than those with a score of 0 to 2. The CHAI further stratified outcomes for persons with no clinically recognizable comorbidities.
Substantial variation exists in the CHAI according to sociodemographic characteristics and geographic regions. The CHAI could identify Chinese elderly adults with low risk of adverse outcomes and provide incremental value for risk prediction beyond clinically diagnosed comorbidities.
根据社会人口学特征和地理区域,描述中国老年人健康老龄化指数(CHAI)的分布情况,并探讨 CHAI 与 4 年内死亡率、残疾和功能受限之间的关系。
全国代表性队列研究。
中国健康与退休纵向研究。
60 岁及以上的中国成年人(N=3740)。
根据性别特异的三分位或临床相关切点,将 CHAI 的 6 个组成部分(收缩压、呼气峰流速、电话认知状态测试、估算肾小球滤过率、空腹血糖、C 反应蛋白)评分 0(最健康)、1 和 2(最不健康),并将其相加构建 CHAI(范围 0-12)。
平均 CHAI 评分为 5.6;5.7%的人得分为 0-2(最健康),23.0%的人得分为 3 或 4,37.5%的人得分为 5 或 6,33.8%的人得分为 7-12(最不健康)。年龄较小、受教育程度较高和已婚的参与者更有可能具有理想的 CHAI 特征(评分 0-2)。理想 CHAI 特征的年龄调整患病率从南方的 1.7%到北方的 8.1%不等。经过多变量调整后,CHAI 评分为 3-12 的人与评分 0-2 的人相比,死亡率、残疾和功能受限的几率明显更高。CHAI 进一步对无临床可识别合并症的人群进行了分层。
根据社会人口学特征和地理区域,CHAI 存在显著差异。CHAI 可以识别出发生不良结局风险较低的中国老年人群体,并在临床诊断合并症之外提供额外的风险预测价值。