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[经皮穴位电刺激对腹腔镜胆囊切除术后早期恢复质量的影响]

[Effects of transcutaneous electrical acupoint stimulation on quality of recovery during early period after laparoscopic cholecystectomy].

作者信息

Mi Zhihua, Gao Ju, Chen Xiaoping, Ge Yali, Lu Kaixin

机构信息

Clinical Medical School of Yangzhou University ,Yangzhou 225001, Jiangsu Province, China; Department of Anesthesiology, Subei People's Hospital of Jiangsu Province, Yangzhou 225001.

Department of Anesthesiology, Subei People's Hospital of Jiangsu Province, Yangzhou 225001.

出版信息

Zhongguo Zhen Jiu. 2018 Mar 12;38(3):256-60. doi: 10.13703/j.0255-2930.2018.03.007.

Abstract

OBJECTIVE

To evaluate the effect of transcutaneous electrical acupoint stimulation (TEAS) on the quality of recovery during the early period after laparoscopic cholecystectomy and the dosage of anesthetic and analgesic.

METHODS

One hundred patients who received laparoscopic cholecystectomy with gradeⅠand Ⅱ of American Society of Anesthesiologists (ASA) criteria were randomly assigned into an observation group and a control group according to random number table, 50 cases in each group. The patients in the two groups were treated with conventional endotracheal intubation anesthesia, anesthesia induction and maintenance. The patients in the observation group were treated with TEAS (2 Hz/100 Hz, 8 to 12 mA) at bilateral Hegu (LI 4) and Neiguan (PC 6), as well as Zusanli (ST 36) and the non-acupoint 2 outboard from Zusanli (ST 36) from 30 min before anesthesia induction to the end of operation. The patients in the control group were applied by stimulation electrode in the corresponding points without electrical stimulation. The dosage of intraoperative remifentanil and the analgesic dosage of dezocine for postoperation were recorded. The recovery time, extubation time, the changes of heart rate (HR) and mean arterial pressure (MAP) during extubation were recorded. The quality of recovery was assessed by the quality of recovery-40 questionnaire (QoR-40) 1 day before surgery (T),and 4 h (T), 8 h (T), 24 h (T), 48 h (T) after surgery. The patient's cognitive function was assessed by mini-mental state examination (MMSE) scale at the 5 time points. The incidences of postoperative nausea and vomiting were recorded at T through T.

RESULTS

The dosages of intraoperative remifentanil and dezocine in the observation group were less than those in the control group; the recovery time and extubation time were shorter than those in the control group; the HR of extubation was lower than that in the control group (all <0.05). There was no statistic difference about MAP between the two groups (>0.05). Compared with T, the total scores of QoR-40 decreased in the two groups at T, T, T (all <0.05), and the total scores in the observation group were higher than those in the control group (all <0.05). The emotional state, physical comfort, psychological support, self-care ability, pain scores at T in the observation group and at T, T, T in the control group were lower than those at T (all <0.05). The emotional state, physical comfort, psychological support, self-care ability, pain scores in the observation group were higher than those in the control group at T, T, T (all <0.05). Compared with T, the MMSE scores in the two groups decreased at T and T (all <0.05). At T, T, T, the MMSE scores in the observation group were higher than those in the control group (all <0.05). At T and T, the incidence rates of nausea and vomiting were 22.0% (11/50), 12.0% (6/50) respectively in the observation group, which were lower than 32.0% (16/50) and 24.0% (12/50) in the control group (both <0.05). At T and T, the incidence rates of nausea and vomiting were 6.0% (3/50), 2.0% (1/50) respectively in the observation group, which were not significantly different from 8.0% (4/50) and 4.0% (2/50) in the control group (both >0.05).

CONCLUSION

TEAS can improve the quality of recovery during the early period after laparoscopic cholecystectomy and reduce the dosage of anesthetic and analgesic.

摘要

目的

评价经皮穴位电刺激(TEAS)对腹腔镜胆囊切除术后早期恢复质量及麻醉镇痛药用量的影响。

方法

选取100例符合美国麻醉医师协会(ASA)Ⅰ、Ⅱ级标准行腹腔镜胆囊切除术的患者,按随机数字表法随机分为观察组和对照组,每组50例。两组患者均采用常规气管内插管麻醉,进行麻醉诱导和维持。观察组患者于麻醉诱导前30分钟至手术结束,在双侧合谷(LI 4)、内关(PC 6)以及足三里(ST 36)和足三里(ST 36)外侧旁开2寸的非穴位处给予TEAS(2 Hz/100 Hz,8至12 mA)。对照组患者在相应穴位处应用刺激电极但不给予电刺激。记录术中瑞芬太尼用量及术后地佐辛镇痛用量。记录恢复时间、拔管时间、拔管时心率(HR)和平均动脉压(MAP)的变化。术前1天(T0)及术后4小时(T1)、8小时(T2)、24小时(T3)、48小时(T4)采用恢复质量-40问卷(QoR-40)评估恢复质量。在5个时间点采用简易精神状态检查表(MMSE)评估患者认知功能。记录T0至T4时间段术后恶心呕吐的发生率。

结果

观察组术中瑞芬太尼及地佐辛用量少于对照组;恢复时间和拔管时间短于对照组;拔管时HR低于对照组(均P<0.05)。两组间MAP比较差异无统计学意义(P>0.05)。与T0比较,两组在T1、T2、T3时QoR-40总分均降低(均P<0.05),且观察组总分高于对照组(均P<0.05)。观察组T1时及对照组T2、T3、T4时的情绪状态、身体舒适度、心理支持、自我护理能力、疼痛评分均低于T0时(均P<0.05)。观察组T2、T3、T4时的情绪状态、身体舒适度、心理支持、自我护理能力、疼痛评分高于对照组(均P<0.05)。与T0比较,两组在T1、T2时MMSE评分降低(均P<0.05)。在T2、T3时,观察组恶心呕吐发生率分别为22.0%(11/50)、12.0%(6/50),低于对照组的32.0%(16/50)、24.0%(12/50)(均P<0.05)。在T4、T5时,观察组恶心呕吐发生率分别为6.0%(3/50)、2.0%(1/50),与对照组的8.0%(4/50)、4.0%(2/50)比较差异无统计学意义(均P>0.05)。

结论

TEAS可提高腹腔镜胆囊切除术后早期恢复质量,减少麻醉镇痛药用量。

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