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基于反应的比率型荧光传感器,用于检测细胞和细菌中的 Hg(ii) 离子。

A reaction-based ratiometric fluorescent sensor for the detection of Hg(ii) ions in both cells and bacteria.

机构信息

Key Laboratory of Green Chemistry and Technology, Ministry of Education, College of Chemistry Sichuan University, 29, Wangjiang Road, Chengdu, Sichuan Province, China.

出版信息

Chem Commun (Camb). 2018 May 10;54(39):4955-4958. doi: 10.1039/c8cc01031e.

Abstract

A novel reaction-based fluorescent probe (ATC-Hg) was designed and synthesized via the "covalent assembly" principle, which exhibited excellent selectivity and high sensitivity for Hg2+ and CH3Hg+. Moreover, it is the first Hg(ii) sensitive fluorescent probe that has been successfully applied in imaging in both cells and Escherichia coli.

摘要

一种基于新型反应的荧光探针(ATC-Hg)被设计并通过“共价组装”原理合成,它对 Hg2+ 和 CH3Hg+ 表现出优异的选择性和高灵敏度。此外,它是第一个成功应用于细胞和大肠杆菌成像的 Hg(ii) 敏感荧光探针。

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