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一种在水相介质、活细胞和生物体中检测 Hg 的红色荧光探针,具有较大的斯托克斯位移。

A red-emitting fluorescent probe for the detection of Hg in aqueous medium, living cells and organisms with a large Stokes shift.

机构信息

College of Chemistry & Chemical Engineering, Central South University, Changsha, Hunan Province 410083, P. R. China.

出版信息

Org Biomol Chem. 2018 Jul 11;16(27):5036-5042. doi: 10.1039/c8ob00831k.

Abstract

A red-emitting fluorescent probe has been developed for the selective and sensitive detection of Hg2+. With the addition of Hg2+, the solution of probe 1 displayed a remarkable fluorescence enhancement (102 fold) with λemmax = 625 nm and a large Stokes shift (150 nm). The detection limit of this probe was as low as 7.1 nM based on S/N = 3. This probe exhibited a good performance in detecting Hg2+ in real water samples, living cells and organisms.

摘要

一种红色荧光探针被开发出来,用于选择性和灵敏地检测 Hg2+。随着 Hg2+ 的加入,探针 1 的溶液显示出显著的荧光增强(102 倍),λemmax = 625nm,Stokes 位移大(150nm)。该探针的检测限低至 7.1 nM(基于 S/N = 3)。该探针在实际水样、活细胞和生物中检测 Hg2+ 时表现出良好的性能。

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