埃塞俄比亚南部接受产前护理的孕妇弓形虫感染血清阳性率。
Seroprevalence of Toxoplasma gondii infection in pregnant women attending antenatal care in southern Ethiopia.
作者信息
Jula J, Girones G, Edao B, Deme C, Cebrian J, Butrón L, Reyes F, Ramos J M
机构信息
José M Ramos, Department of Internal Medicine, Hospital General Universitario de Alicante C/Pintor Baeza 10, 03010 Alicante, Spain.
出版信息
Rev Esp Quimioter. 2018 Aug;31(4):363-366. Epub 2018 Jul 4.
OBJECTIVE
The aim of the study was to assess the prevalence and possible risk factors of Toxoplasma gondii (toxoplasmosis) infection in pregnant women attending antenatal care at Gambo General Rural Hospital, southern Ethiopia.
METHODS
Hospital-based, prospective cross-sectional study. We collected 401 serum samples from September 1 to October 30, 2015, along with sociodemographic data and data on potential risk factors, using a simple random sampling technique.
RESULTS
The overall seroprevalence of T. gondii in pregnant women (mean age 23.1 years) was 23.9% (95% confidence interval [CI] 20.0, 28.3). We did not find any significant risk factors associated with seropositivity in relation with participants' level of education; occupation; contact with cats; consumption of raw or uncooked meat, vegetables, or milk; or type of flooring (soil versus cement) at home. The women who were aware of the risk of toxoplasma infection on the fetus had fewer T. gondii antibodies. Drinking unsafe water was as-sociated with a higher risk of toxoplasmosis (p = 0.08).
CONCLUSIONS
The seroprevalence of toxoplasmosis among pregnant women was relatively lower.
目的
本研究旨在评估埃塞俄比亚南部甘博综合乡村医院接受产前检查的孕妇弓形虫（弓形虫病）感染的患病率及可能的危险因素。
方法
基于医院的前瞻性横断面研究。我们于2015年9月1日至10月30日，采用简单随机抽样技术收集了401份血清样本，以及社会人口统计学数据和潜在危险因素的数据。
结果
孕妇（平均年龄23.1岁）弓形虫总体血清阳性率为23.9%（95%置信区间[CI]20.0，28.3）。我们未发现与血清阳性相关的任何显著危险因素，包括参与者的教育水平、职业、与猫的接触、生肉或未煮熟的肉、蔬菜或牛奶的消费，或家中地板类型（泥土与水泥）。知晓弓形虫感染对胎儿有风险的女性弓形虫抗体较少。饮用不安全水与弓形虫病风险较高相关（p = 0.08）。
结论
孕妇弓形虫病血清阳性率相对较低。
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