Paul Sima, Ghoshal Kakali, Bhattacharyya Maitree, Maiti Dilip K
Department of Chemistry, University of Calcutta, 92 Acharya Prafulla Chandra Road, Kolkata 700009, India.
Department of Biochemistry, University of Calcutta, 35 Ballygunge Circular Road, Kolkata 700019, India.
ACS Omega. 2017 Dec 31;2(12):8633-8639. doi: 10.1021/acsomega.7b01218. Epub 2017 Dec 4.
A rapid fluorescent probe based on the conjugate of chromone and benzothiazole moiety was presented, which could selectively respond to HSO over other common anions and thiols. The function of the probe relies on nucleophilic addition to break down the π-conjugation. The probe can be used as a signal tool to determine HSO levels in sugar-based food and living cells.
报道了一种基于色酮和苯并噻唑部分共轭物的快速荧光探针,它能选择性地响应HSO,而不响应其他常见阴离子和硫醇。该探针的功能依赖亲核加成来破坏π共轭。该探针可作为一种信号工具,用于测定糖类食品和活细胞中的HSO水平。