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中国沈阳的急性中毒:一项2012年至2016年的回顾性描述性研究。

Acute poisoning in Shenyang, China: a retrospective and descriptive study from 2012 to 2016.

作者信息

Zhang Yajie, Yu Boxin, Wang Nana, Li Tiegang

机构信息

Emergency Department, Shengjing Hospital of China Medical University, Shenyang, China.

Gerontology Department, Shengjing Hospital of China Medical University, Shenyang, China.

出版信息

BMJ Open. 2018 Aug 29;8(8):e021881. doi: 10.1136/bmjopen-2018-021881.

Abstract

OBJECTIVES

Up-to-date information on the patterns of acute poisoning is crucial for the proper management of poisoning events. The objectives of this study were to analyse the characteristics of patients suffering from acute poisoning admitted to the emergency department (ED) in a tertiary medical centre in Northeast China and to compare these characteristics with those of a previous comparable study.

DESIGN

Retrospective and descriptive study.

SETTING

Data were collected from the hospital information system in Shengjing Hospital, China, from January 2012 to December 2016.

PARTICIPANTS

All cases aged ≥11 years old with a diagnosis of acute poisoning.

RESULTS

In total, 5009 patients aged ≥11 years presented to the ED with acute poisoning during the study period. The average age of the patients was 36.0±15.1 years and over half (52.7%) were in the 20-39age group. The female to male ratio was 1.2:1. Patients with acute poisoning mainly lived in rural areas rather than in urban areas. The majority of patients consumed poison as suicide attempts (56.7%). Men were more commonly poisoned by drug abuse than women, but women outnumbered men in suicidal poisoning. The most common form of poison intake was ingestion (oral intake; 86.2%). The five most common toxic agent groups, in descending order, were therapeutic drugs (32.6%), pesticides (26.9%), alcohol (20.7%), fumes/gases/vapours (11.4%) and chemicals (3.6%). Sedatives/hypnotics in the therapeutic drugs group and paraquat in the pesticides group were the most common toxic agents, respectively. The mortality rate of study participants was 1.3%, with 64 deaths.

CONCLUSIONS

The results of this study indicate the need to strengthen education on the rational and safe use of drugs in Shenyang.

摘要

目的

获取最新的急性中毒模式信息对于中毒事件的妥善处理至关重要。本研究的目的是分析中国东北地区一家三级医疗中心急诊科收治的急性中毒患者的特征,并将这些特征与之前一项类似研究的结果进行比较。

设计

回顾性描述性研究。

地点

数据收集自中国盛京医院2012年1月至2016年12月的医院信息系统。

参与者

所有年龄≥11岁且诊断为急性中毒的病例。

结果

在研究期间,共有5009名年龄≥11岁的患者因急性中毒就诊于急诊科。患者的平均年龄为36.0±15.1岁,超过半数(52.7%)在20 - 39岁年龄组。男女比例为1.2:1。急性中毒患者主要居住在农村地区而非城市地区。大多数患者中毒是企图自杀(56.7%)。男性因药物滥用中毒的情况比女性更常见,但在自杀性中毒方面女性多于男性。最常见的中毒摄入形式是吞服(经口摄入;86.2%)。按降序排列,五种最常见的毒物类别为治疗性药物(32.6%)、农药(26.9%)、酒精(20.7%)、烟雾/气体/蒸气(11.4%)和化学品(3.6%)。治疗性药物组中的镇静剂/催眠药和农药组中的百草枯分别是最常见的毒物。研究参与者的死亡率为1.3%,有64例死亡。

结论

本研究结果表明沈阳需要加强关于合理安全用药的教育。

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