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肌少症:定义和诊断的欧洲共识修订版。

Sarcopenia: revised European consensus on definition and diagnosis.

机构信息

Servicio de Geriatría, Hospital Universitario Ramón y Cajal (IRYCIS), Madrid, Spain.

Department of Internal Medicine, Division of Geriatrics, Istanbul Medical School, Istanbul University, Istanbul, Turkey.

出版信息

Age Ageing. 2019 Jan 1;48(1):16-31. doi: 10.1093/ageing/afy169.

Abstract

BACKGROUND

in 2010, the European Working Group on Sarcopenia in Older People (EWGSOP) published a sarcopenia definition that aimed to foster advances in identifying and caring for people with sarcopenia. In early 2018, the Working Group met again (EWGSOP2) to update the original definition in order to reflect scientific and clinical evidence that has built over the last decade. This paper presents our updated findings.

OBJECTIVES

to increase consistency of research design, clinical diagnoses and ultimately, care for people with sarcopenia.

RECOMMENDATIONS

sarcopenia is a muscle disease (muscle failure) rooted in adverse muscle changes that accrue across a lifetime; sarcopenia is common among adults of older age but can also occur earlier in life. In this updated consensus paper on sarcopenia, EWGSOP2: (1) focuses on low muscle strength as a key characteristic of sarcopenia, uses detection of low muscle quantity and quality to confirm the sarcopenia diagnosis, and identifies poor physical performance as indicative of severe sarcopenia; (2) updates the clinical algorithm that can be used for sarcopenia case-finding, diagnosis and confirmation, and severity determination and (3) provides clear cut-off points for measurements of variables that identify and characterise sarcopenia.

CONCLUSIONS

EWGSOP2's updated recommendations aim to increase awareness of sarcopenia and its risk. With these new recommendations, EWGSOP2 calls for healthcare professionals who treat patients at risk for sarcopenia to take actions that will promote early detection and treatment. We also encourage more research in the field of sarcopenia in order to prevent or delay adverse health outcomes that incur a heavy burden for patients and healthcare systems.

摘要

背景

2010 年,欧洲老年人肌肉减少症工作组(EWGSOP)发布了肌肉减少症定义,旨在促进识别和护理肌肉减少症患者方面的进展。2018 年初,工作组再次开会(EWGSOP2),以更新最初的定义,以反映过去十年中积累的科学和临床证据。本文介绍了我们的最新发现。

目的

提高研究设计、临床诊断的一致性,并最终改善肌肉减少症患者的护理。

建议

肌肉减少症是一种肌肉疾病(肌肉衰竭),源于一生中累积的不良肌肉变化;肌肉减少症在老年成年人中很常见,但也可能在生命早期发生。在这份关于肌肉减少症的更新共识文件中,EWGSOP2:(1)侧重于低肌肉力量作为肌肉减少症的一个关键特征,使用检测低肌肉量和质量来确认肌肉减少症的诊断,并确定身体机能差是严重肌肉减少症的指征;(2)更新了可用于肌肉减少症病例发现、诊断和确认以及严重程度确定的临床算法;(3)为识别和描述肌肉减少症的变量提供明确的截断值。

结论

EWGSOP2 的更新建议旨在提高对肌肉减少症及其风险的认识。通过这些新建议,EWGSOP2 呼吁治疗有肌肉减少症风险的患者的医疗保健专业人员采取行动,以促进早期发现和治疗。我们还鼓励在肌肉减少症领域开展更多研究,以预防或延迟对患者和医疗系统造成沉重负担的不良健康后果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a795/6322506/d8a5bc335874/afy169f01.jpg

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