Department of Social Medicine and Health Education, School of Public Health, Nanjing Medical University, 101 Longmian Ave, Nanjing, 211166, China.
Center for Health Policy and Management Studies, Nanjing University, 22 Hankou Road, Nanjing, 210093, China.
BMC Public Health. 2018 Oct 12;18(1):1174. doi: 10.1186/s12889-018-6086-1.
This study aimed to explore the effects of (body mass index) BMI on health related quality of life (HRQoL) among the elderly in Jiangsu, China.
A total of 10,257 community dwelling elderly (≥60 years old) were enrolled in a cross-sectional study. HRQoL was measured via the Eq-5d-3 L. Chi-square tests and one-way ANOVA analyses were used to compare the frequencies and scores of Eq-5d responses among different BMI groups (defined as "underweight", "normal weight", "overweight" and "obese"). Logistic regression analyses were conducted to examine the associations between BMI and HRQoL.
Among the subjects, the proportion of "normal weight", "underweight", "overweight" and "obese" were 66.0, 8.3, 23.1, and 2.6%, respectively. The score of the Eq-5d index among total participants was 0.8036 and the Visual Analog Scale (VAS) score was 75.47. For both the responses frequency and scores of Eq-5d-3 L, there were significant differences among BMI groups (P < 0.001). The Logistic regression model showed that both in men and women, underweight elderly were more likely to suffer low HRQoL. The adjusted odds ratio (OR) with a 95% confidence interval (CI) for Eq-5d index/VAS was 2.03 (1.48, 2.79)/1.83 (1.34, 2.50) in men and 1.47(1.09,1.98)/1.52(1.20,1.91) in women. Overweight women more likely to have a low Eq-5d index, while overweight men were less likely to have a low Eq-5d VAS.
This study shows that underweight is an explicit risk factor of low HRQoL in both the male and female elderly, while the effect of overweight on low HRQoL varies slightly by gender.
本研究旨在探讨(体重指数)BMI 对中国江苏老年人健康相关生活质量(HRQoL)的影响。
共纳入 10257 名居住在社区的老年人(≥60 岁)进行横断面研究。HRQoL 通过 Eq-5d-3L 进行测量。采用卡方检验和单因素方差分析比较不同 BMI 组(定义为“消瘦”、“正常体重”、“超重”和“肥胖”)的 Eq-5d 反应频率和得分。采用 logistic 回归分析 BMI 与 HRQoL 之间的关系。
在研究对象中,“正常体重”、“消瘦”、“超重”和“肥胖”的比例分别为 66.0%、8.3%、23.1%和 2.6%。总参与者的 Eq-5d 指数得分为 0.8036,视觉模拟量表(VAS)评分为 75.47。无论是 Eq-5d-3L 的反应频率还是得分,BMI 组之间均存在显著差异(P<0.001)。Logistic 回归模型显示,消瘦的老年人在男性和女性中都更容易出现低 HRQoL。调整后的比值比(OR)及其 95%置信区间(CI)为 Eq-5d 指数/VAS 分别为男性 2.03(1.48,2.79)/1.83(1.34,2.50)和女性 1.47(1.09,1.98)/1.52(1.20,1.91)。超重的女性更有可能出现低 Eq-5d 指数,而超重的男性出现低 Eq-5d VAS 的可能性较小。
本研究表明,消瘦是男性和女性老年人低 HRQoL 的明确危险因素,而超重对低 HRQoL 的影响因性别而异。