Department of Pharmaceutical Sciences, Universidade Federal da Paraíba, 58051-970 João Pessoa, Paraíba, Brazil.
Department of Biomedicine, University Center INTA-UNINTA, 62050-130 Sobral, Ceará, Brazil.
Oxid Med Cell Longev. 2018 Oct 22;2018:3957262. doi: 10.1155/2018/3957262. eCollection 2018.
The bioactive compounds found in foods and medicinal plants are attractive molecules for the development of new drugs with action against several diseases, such as those associated with inflammatory processes, which are commonly related to oxidative stress. Many of these compounds have an appreciable inhibitory effect on oxidative stress and inflammatory response, and may contribute in a preventive way to improve the quality of life through the use of a diet rich in these compounds. Eugenol is a natural compound that has several pharmacological activities, action on the redox status, and applications in the food and pharmaceutical industry. Considering the importance of this compound, the present review discusses its anti-inflammatory and antioxidant properties, demonstrating its mechanisms of action and therapeutic potential for the treatment of inflammatory diseases.
食物和药用植物中的生物活性化合物是开发新药物的有吸引力的分子,这些新药物可以对抗多种疾病,如与炎症过程相关的疾病,这些疾病通常与氧化应激有关。这些化合物中的许多对氧化应激和炎症反应具有明显的抑制作用,并且可能通过使用富含这些化合物的饮食以预防的方式有助于提高生活质量。丁香酚是一种天然化合物,具有多种药理活性,可影响氧化还原状态,并且在食品和制药行业中有应用。鉴于该化合物的重要性,本综述讨论了其抗炎和抗氧化特性,展示了其作用机制和治疗炎症性疾病的治疗潜力。