藏红花（L.）：作为一种抗抑郁剂。
Saffron ( L.): As an Antidepressant.
作者信息
Siddiqui Mohammad J, Saleh Mohammed S M, Basharuddin Siti N B Binti, Zamri Siti H Binti, Mohd Najib Mohd H Bin, Che Ibrahim Muhammad Z Bin, Binti Mohd Noor Nur A, Binti Mazha Hanin N, Mohd Hassan Norazian, Khatib Alfi
机构信息
Department of Pharmaceutical Chemistry, Kulliyyah of Pharmacy, International Islamic University Malaysia, Kuantan, Pahang, Malaysia.
出版信息
J Pharm Bioallied Sci. 2018 Oct-Dec;10(4):173-180. doi: 10.4103/JPBS.JPBS_83_18.
Saffron, (Iridaceae), is a perennial herb, which earned its popularity as both medicine and spice. It is an inhabitant of different mountainous regions of Asia Minor to Greece, Western Asia, Egypt, and India. The benefits of saffron as an antidepressant are well-documented. Almost 150 volatile and nonvolatile compounds are obtained from the chemical analysis of this plant. Fewer than 50 constituents elucidated and identified so far showed phytochemical characteristics. The major bioactive compounds identified are safranal, crocin, and picrocrocin, which are responsible for its aroma as well as its bitter taste. This review is an attempt to encompass the methods of analysis and pharmacodynamic and pharmacokinetic properties of saffron followed by its efficacious and safe potential.
藏红花（鸢尾科）是一种多年生草本植物，作为药物和香料都颇受欢迎。它生长于从小亚细亚到希腊、西亚、埃及和印度的不同山区。藏红花作为抗抑郁药的益处有充分的文献记载。通过对这种植物的化学分析得到了近150种挥发性和非挥发性化合物。到目前为止，已阐明和鉴定的成分不到50种，这些成分具有植物化学特征。鉴定出的主要生物活性化合物是藏红花醛、藏红花素和苦藏花素，它们赋予了藏红花香气和苦味。本综述旨在涵盖藏红花的分析方法、药效学和药代动力学特性，以及其有效和安全的潜力。
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