Research School of Biology, The Australian National University, Acton, ACT, Australia.
PLoS Biol. 2018 Dec 20;16(12):e3000048. doi: 10.1371/journal.pbio.3000048. eCollection 2018 Dec.
This study highlights how the mortality plateau in Barbi and colleagues can be generated by low-frequency, randomly distributed age-misreporting errors. Furthermore, sensitivity of the late-life mortality plateau in Barbi and colleagues to the particular age range selected for regression is illustrated. Collectively, the simulation of age-misreporting errors in late-life human mortality data and a less-specific model choice than that of Barbi and colleagues highlight a clear alternative hypothesis to explanations based on evolution, the cessation of ageing, and population heterogeneity.
本研究强调了低频、随机分布的年龄误报误差如何导致巴比和同事的死亡率高原现象。此外,还说明了巴比和同事的老年死亡率高原现象对回归选择的特定年龄范围的敏感性。总的来说,在老年人类死亡率数据中模拟年龄误报误差,以及选择比巴比和同事更不具体的模型,突出了一个明确的替代假设,即基于进化、衰老停止和人口异质性的解释。